| Identification | More | [Name]
(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide | [CAS]
52509-14-5 | [Synonyms]
(1,3-DIOXOLAN-2-YLMETHYL)TRIPHENYLPHOSPHONIUM BROMIDE
(1,3-DIOXOLANE-2-YL METHYL) TRIPHENYL PHOSPHONIUM BROMIDE
LABOTEST-BB LT00233112
TRIPHENYL-1,3-DIOXOLAN-2-YLMETHYL-PHOSPHONIUM BROMIDE
2-(1,3)-DIOXOLANE-2-YL-METHYLTRIPHENYLPHOSPHONIUM BROMIDE
Phosphonium, (1,3-dioxolan-2-ylmethyl)triphenyl-, bromide
(1,3-DIOXOLAN-2-YLMETHYL)TRIPHENYLPHOSPHONIUM BROMIDE 98%
(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium bromide, 98 %
1,3-Dioxolan-2-ylmethyl-triphenylphosphanium bromide
Triphenyl(1,3-dioxolane-2-ylmethyl)phosphonium·bromide | [EINECS(EC#)]
257-977-3 | [Molecular Formula]
C22H22BrO2P | [MDL Number]
MFCD00011966 | [Molecular Weight]
429.29 | [MOL File]
52509-14-5.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light brown granular powder | [Melting point ]
193-195 °C(lit.)
| [storage temp. ]
Store below +30°C. | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Powder or Crystals | [color ]
White to light brown | [Water Solubility ]
Soluble in water (20°C). | [Sensitive ]
Hygroscopic | [InChIKey]
FRHRVQQUICVJDG-UHFFFAOYSA-M | [CAS DataBase Reference]
52509-14-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
3
| [HS Code ]
29329970 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light brown granular powder | [Uses]
(1,3-Dioxolan-2-ylmethyl)triphenylphosphonium Bromide is used as a reactant in the synthesis of ketolides methyloxoerythromycins with antibacterial activity as highly potent against macrolide-resistant and susceptible respiratory pathogens. | [reaction suitability]
reaction type: C-C Bond Formation | [Purification Methods]
Wash the crystals with Et2O, dry them in a vacuum and recrystallise them from CH2Cl2/dry Et2O to give prisms m 172-174o, which is raised to 191.5-193o on drying at 56o/0.5mm. [Cresp et al. J Chem Soc, Perkin Trans 1 37 1974.] |
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