| Identification | More | [Name]
Epinephrine bitartrate | [CAS]
51-42-3 | [Synonyms]
1-(3,4-DIHYDROXYPHENYL)-2-(METHYLAMINO)ETHANOL-(+)-BITARTRATE
(-)-ADRENALIN (+)BITARTRATE SALT
ADRENALINE ACID TARTRATE
ADRENALINE BITARTRATE
ADRENALINE-(+)-BITARTRATE
ADRENALINE HYDROGEN TARTRATE
ADRENAL, RAT
EPINEPHRINE ACID TARTRATE
EPINEPHRINE BITARTRATE
(-)-EPINEPHRINE (+)BITARTRATE SALT
(-)-EPINEPHRINE-(+)-HYDROGEN TARTRATE
L-1-(3,4-DIHYDROXYPHENYL)-2-METHYLAMINOETHANOL BITARTRATE
L-3,4-DIHYDROXY-ALPHA-[(METHYLAMINO)METHYL]BENZYL ALCOHOL BITARTRATE
L-3,4-DIHYDROXY-ALPHA-(METHYLAMINOMETHYL)BENZYL ALCOHOL D-HYDROGEN BITARTRATE SALT
L-ADRENALINE BITARTRATE
L-ADRENALINE (+)-BITARTRATE SALT
L-ADRENALINE D-HYDROGENTARTRATE
L-ADRENALINE HYDROGEN TARTRATE
L-(-)-EPINEPHRINE-(+)-BITARTRATE
L-EPINEPHRINE BITARTRATE | [EINECS(EC#)]
200-097-1 | [Molecular Formula]
C13H19NO9 | [MDL Number]
MFCD00035077 | [Molecular Weight]
333.29 | [MOL File]
51-42-3.mol |
| Chemical Properties | Back Directory | [Appearance]
solid | [Melting point ]
~155 °C (dec.)
| [refractive index ]
-16.5 ° (C=2, H2O) | [storage temp. ]
2-8°C
| [solubility ]
H2O: soluble
| [form ]
solid
| [color ]
white
| [Stability:]
Stable. Incompatible with bases, oxidizing agents, iron, iron salts, copper, copper alloys. | [Merck ]
13,3650 | [InChI]
InChI=1S/C9H13NO3.C4H6O6/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;5-1(3(7)8)2(6)4(9)10/h2-4,9-13H,5H2,1H3;1-2,5-6H,(H,7,8)(H,9,10) | [InChIKey]
YLXIPWWIOISBDD-NDAAPVSOSA-N | [SMILES]
OC1=C(O)C=CC(C(CNC)O)=C1.OC(C(C(C(O)=O)O)O)=O | [CAS DataBase Reference]
51-42-3(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
T+ | [Risk Statements ]
R28:Very Toxic if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S36/37:Wear suitable protective clothing and gloves .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2811 6.1/PG 1
| [WGK Germany ]
3
| [RTECS ]
DO3500000
| [F ]
8-10-23 | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [HS Code ]
29379000 |
| Hazard Information | Back Directory | [Description]
Epinephrine bitartrate is the bitartrate salt form of epinephrine, a direct-acting sympathomimetic amine with bronchodilator and vasoconstricting activity. Epinephrine bitartrate acts on both alpha and beta-adrenergic receptors. By stimulating alpha-adrenergic receptors locally, this agent causes vasoconstriction and reduces vascular blood flow. Administered in the conjunctiva, epinephrine bitartrate induces vasoconstriction and decreases the production of aqueous humor mediated through alpha-adrenergic receptors. This agent relaxes bronchial smooth muscle through its beta-stimulating actions and causes bronchodilation. | [Chemical Properties]
solid | [Uses]
adrenergic agonist, bronchodilator, antiglaucoma agent | [Uses]
vasodilator | [Brand name]
Bronitin (Wyeth); Medihaler-EPI (3MPharmaceuticals). | [General Description]
α,β-Adrenergic receptor agonist. Has positive chronotropic and inotropic effects on heart muscle. Activates adenylate cyclase to generate cAMP from ATP. | [Biochem/physiol Actions]
Primary Targetα,β-Adrenergic receptor agonist | [storage]
Store at 2-8°C |
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