| Identification | More | [Name]
DIPHENYL PHOSPHITE | [CAS]
4712-55-4 | [Synonyms]
DIPHENYL HYDROGEN PHOSPHITE
DIPHENYL PHOSPHITE
DIPHENYL PHOSPHONATE
PHOSPHONIC ACID DIPHENYL ESTER
PHOSPHOROUS ACID DIPHENYL ESTER
Diphenoxyphosphine oxide
Doverphos 213
Doverphos DPP
Phenyl phosphonate ((PhO)2HPO)
Weston DPP
Diphenyl phosphite, contains varying amounts of phenol and (C6H5)3P
Diphenyl phosphite, contains varying amounts of phenol and (C6H5O)3P
Phosphorous acid diphenyl
Phosphonic acid diphenyl | [EINECS(EC#)]
225-202-8 | [Molecular Formula]
C12H11O3P | [MDL Number]
MFCD00044497 | [Molecular Weight]
234.19 | [MOL File]
4712-55-4.mol |
| Chemical Properties | Back Directory | [Appearance]
clear liquid | [Melting point ]
12 °C (lit.) | [Boiling point ]
218-219 °C/26 mmHg (lit.) | [density ]
1.223 g/mL at 25 °C(lit.)
| [vapor density ]
8.1 (vs air)
| [vapor pressure ]
5 mm Hg ( 140 °C)
| [refractive index ]
n20/D 1.558(lit.)
| [Fp ]
350 °F
| [storage temp. ]
Inert atmosphere,2-8°C | [form ]
Liquid | [color ]
Clear | [Specific Gravity]
1.223 | [BRN ]
2051909 | [InChIKey]
OGBPILLJZSJJRC-UHFFFAOYSA-N | [LogP]
2.4 at 25℃ and pH7 | [CAS DataBase Reference]
4712-55-4(CAS DataBase Reference) | [EPA Substance Registry System]
Diphenyl phosphite (4712-55-4) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed.
R37/38:Irritating to respiratory system and skin .
R41:Risk of serious damage to eyes. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S39:Wear eye/face protection . | [RIDADR ]
1760 | [WGK Germany ]
3
| [F ]
21 | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29209090 |
| Hazard Information | Back Directory | [Chemical Properties]
clear liquid | [Uses]
Diphenyl Phosphite is a reactant used in the synthesis of α-hydroxyphosphonates and α-hydroxyphosphinates for their antioxidant and antimicrobial activity. | [Synthesis]
In a three-necked round-bottomed flask equipped with a mechanical stirrer, a reflux condenser and a dropping funnel, the first P-O component (PIII-OH) is added under nitrogen protection. This P-O component (see column 5 of Table 1) may be selected from H3PO3, monoalkyl phosphite or mixtures thereof and may additionally comprise dialkyl phosphite. Subsequently, the first P-O component is heated to the temperature specified in column 11 of Table 1 (T° step a) for step a). Next, the second P-O component (see column 6 of Table 1) is added while maintaining the appropriate temperature. The mixture was allowed to react for the time indicated in column 13 of Table 1 (reaction time step a), followed by step b). The alcohol R1-OH (see column 3 of Table 1) is then added dropwise while maintaining the temperature specified in column 12 of Table 1 (T° step b). After the mixture was reacted for the time indicated in column 14 of Table 1 (reaction time b), it was cooled to room temperature and analyzed by 31P NMR. | [Purification Methods]
Diphenyl Phosphite can be purified by distillation. Best done in small batches since decomposition frequently occurs. Phenol can be substantially removed by heating at 150 °C at water pump vacuum. | [References]
[1] Patent: EP2581378, 2013, A1. Location in patent: Paragraph 0038; 0039; 0043 |
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