| Identification | More | [Name]
1-(2-Furoyl)piperazine | [CAS]
40172-95-0 | [Synonyms]
1-(2-FURANYLCARBONYL)-PIPERAZINE
1-(2-FUROYL)PIPERAZINE
1-(2-FUROYL)PIPERAZINE HYDROCHLORIDE
2-(2-FUROYL)PIPERAZINE
AKOS B003992
AKOS BB/0087
AKOS BBS-00003689
BIO-FARMA BF003584
(FURAN-2-YL)(PIPERAZIN-1-YL)METHANONE
N-(2-FUROYL)PIPERAZINE
RARECHEM AH CK 0108
TIMTEC-BB SBB003747
N-Furoyl piperazine
1-(2-FUROYL)-PIPERAZINE 97%
1-(2-Furoyl)piperazine,98%
2-furoic piperazide
Piperazine, 1-(2-furanylcarbonyl)-
(2-Furyl)(piperazino) ketone
Piperazino 2-furyl ketone
Piperazino(2-furanyl) ketone | [EINECS(EC#)]
254-823-7 | [Molecular Formula]
C9H12N2O2 | [MDL Number]
MFCD00236012 | [Molecular Weight]
180.2 | [MOL File]
40172-95-0.mol |
| Chemical Properties | Back Directory | [Appearance]
white to light yellow solid | [Melting point ]
67-70 °C(lit.) | [Boiling point ]
137-140°C 0,1mm | [density ]
1.1819 (rough estimate) | [refractive index ]
1.5373 (estimate) | [Fp ]
>230 °F
| [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform, Methanol (Slightly) | [form ]
neat | [pka]
8.37±0.10(Predicted) | [color ]
White to Pale Yellow | [Sensitive ]
Hygroscopic | [BRN ]
880196 | [Stability:]
Very Hygroscopic | [CAS DataBase Reference]
40172-95-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [F ]
10-34 | [Hazard Note ]
Irritant | [HazardClass ]
IRRITANT | [HS Code ]
29339900 |
| Hazard Information | Back Directory | [Chemical Properties]
white to light yellow solid | [Uses]
1-(2-Furoyl)piperazine may be used to synthesize:
- 2-[4-(2-furoyl) piperazin-1-yl]-4-amino-6-benzyloxy-7-methoxyquinazoline hydrochloride monohydrate
- 2-[4-(2-furoyl)piperazin-1-yl]-4-amino-7-benzyloxy-6-methoxyquinazoline hydrochloride monohydrate
- 4-amino-2-[4-(2-furoyl)piperazin-1-yl]-quinazoline hydrochloride
- 6,7-dimethoxy-2-[4-(2-furoyl)-piperazin-1-yl]quinazoline-4-one hydrate
- 1-[2-(3,4-dimethoxyphenyl)ethyl]-4-(2-furoyl)-piperazine hydrogen oxalate
- 1-(3,4-dichlorobenzyl)-4-(2-furoyl)-piperazine hydrogen oxalate
- 4-(9-fluorenyl)-1-(2-furoyl)piperazine
- 2-[4-(2-furoyl)piperazin-1-yl]-benzimidazole hydrochloride hydrate
| [Uses]
2-Furanyl-1-piperazinylmethanone (Terazosin EP Impurity L) was utilized in the fragment-based design of symmetrical bis-benzimidazole as inhibitors of R67 dihydrofolate reductase. | [Uses]
2-Furanyl-1-piperazinylmethanone was utilized in the fragment-based design of symmetrical bis-benzimidazole as inhibitors of R67 dihydrofolate reductase. | [Synthesis Reference(s)]
Journal of Medicinal Chemistry, 20, p. 146, 1977 DOI: 10.1021/jm00211a031 |
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