| Identification | Back Directory | [Name]
8-methylguanosine | [CAS]
36799-17-4 | [Synonyms]
8-methylguanosine
2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-8-methyl-3H-purin-6-one | [Molecular Formula]
C11H15N5O5 | [MDL Number]
MFCD28336924 | [MOL File]
36799-17-4.mol | [Molecular Weight]
297.27 |
| Hazard Information | Back Directory | [Uses]
8-Methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
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