| Identification | More | [Name]
8-BROMOADENOSINE | [CAS]
2946-39-6 | [Synonyms]
(2R,3R,4S,5R)-2-(6-AMINO-8-BROMO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL
6-AMINO-8-BROMOPURINE RIBOSIDE
8-BROMOADENINE-9-BETA-D-RIBOFURANOSIDE
8-BROMOADENOSINE
8-BROMO-D-ADENOSINE
8-BROMOADENOSINE, HPLC PURIFIED, 98% PURE WITH HPLC UV CHROMATOGRAM
6-Amino-8-bromopurine riboside, 8-Bromoadenine-9-β-D-ribofuranoside | [EINECS(EC#)]
220-959-0 | [Molecular Formula]
C10H12BrN5O4 | [MDL Number]
MFCD00005733 | [Molecular Weight]
346.14 | [MOL File]
2946-39-6.mol |
| Chemical Properties | Back Directory | [Appearance]
Off-White Solid | [Melting point ]
210-212 °C (dec.)(lit.) | [Boiling point ]
717.7±70.0 °C(Predicted) | [density ]
1.8171 (rough estimate) | [refractive index ]
1.6400 (estimate) | [storage temp. ]
2-8°C
| [solubility ]
DMSO (Slightly), Methanol (Slightly, Sonicated) | [form ]
powder
| [pka]
12.89±0.70(Predicted) | [color ]
white
| [Water Solubility ]
Soluble in DMSO, and DMF. Insoluble in water. | [Sensitive ]
Air Sensitive | [BRN ]
627737 | [CAS DataBase Reference]
2946-39-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S24/25:Avoid contact with skin and eyes .
S22:Do not breathe dust . | [WGK Germany ]
3
| [F ]
10-23 | [HS Code ]
29349990 |
| Hazard Information | Back Directory | [Description]
8-Bromoadenosine is a nucleotide that is structurally related to adenosine. It can be used as an inhibitor of guanine nucleotide-binding proteins and has shown biological properties in vitro. 8-Bromoadenosine has been shown to inhibit the mitochondrial membrane potential, cytosolic Ca2+, and the synthesis of RNA and protein. 8-Bromoadenosine also inhibits leukemia inhibitory factor (LIF) production by 3T3-L1 preadipocytes and induces apoptosis in T84 cells. | [Chemical Properties]
Off-White Solid | [Uses]
8-Bromoadenosine is an adenosine binding inhibitor. | [Uses]
An adenosine binding inhibitor | [Definition]
ChEBI: 8-Bromoadenosine is a purine nucleoside. |
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