| Identification | More | [Name]
L-Phenylglycine | [CAS]
2935-35-5 | [Synonyms]
H-L-PHG-OH
H-(PHENYL)GLY-OH
H-PHG-OH
L-(+)-2-PHENYLGLYCINE
L-2-PHENYLGLYCINE
L(+)-ALPHA-AMINOPHENYLACETIC ACID
L-ALPHA-AMINOPHENYLACETIC ACID
(+)-L-ALPHA-PHENYLGLYCINE
L-(+)-ALPHA-PHENYLGLYCINE
L-AMINOPHENYLACETIC ACID
L-(+)-PHENYLGLYCINE
L-PHENYLGLYCINE
(+)-PHENYLGLYCINE
PHENYLGLYCINE
PHENYLGLYCINE-L-2
S-(+)-2-AMINOPHENYLACETIC ACID
(S)-(+)-2-PHENYLGLYCINE
(S)-(+)-ALPHA-AMINOPHENYLACETIC ACID
(S)-ALPHA-AMINOPHENYLACETIC ACID
(S)-AMINO-PHENYL-ACETIC ACID | [EINECS(EC#)]
220-909-8 | [Molecular Formula]
C8H9NO2 | [MDL Number]
MFCD00064403 | [Molecular Weight]
151.16 | [MOL File]
2935-35-5.mol |
| Chemical Properties | Back Directory | [Appearance]
White crystalline powder | [Melting point ]
>300 °C(lit.)
| [alpha ]
157 º (c=2, 2N HCl) | [Boiling point ]
273.17°C (rough estimate) | [density ]
1.2023 (rough estimate) | [refractive index ]
158 ° (C=1, 1mol/L HCl) | [Fp ]
150 °C | [storage temp. ]
Store at RT. | [solubility ]
Aqueous Acid, Aqueous Base | [form ]
Fine Crystalline Powder | [pka]
1.83(at 25℃) | [color ]
White | [Optical Rotation]
[α]20/D +155°, c = 1 in 1 M HCl | [Merck ]
14,7291 | [BRN ]
2208675 | [InChIKey]
ZGUNAGUHMKGQNY-ZETCQYMHSA-N | [CAS DataBase Reference]
2935-35-5(CAS DataBase Reference) | [EPA Substance Registry System]
2935-35-5(EPA Substance) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [TSCA ]
Yes | [HS Code ]
29224995 |
| Hazard Information | Back Directory | [Description]
L-Phenylglycine is an amide that belongs to the group of pyridoxal phosphate analogues. It has been shown to be a response element for enzymes and natural compounds in Escherichia coli and Saccharomyces cerevisiae. It inhibits aminotransferase activity, dopamine synthesis, and microbial metabolism in these organisms. This compound also has a structural analysis that includes x-ray diffraction data, which can be used to identify its three-dimensional structure. | [Chemical Properties]
White crystalline powder | [Uses]
L-(+)-2-Phenylglycine is a derivative of Glycine (G615990), the smallest of all the amino acids, and is also used to treat schizophrenia, stroke, and benign prostatic hyperplasia. L-(+)-2-Phenylglycine is also used as an N-linked side chain of an SMTP (Stachybotrys microspora tripenyl phenols) congener, which was potent in enhancing plasminogen activation in S. microspora. | [Definition]
ChEBI: The S stereoisomer of alpha-phenylglycine. | [reaction suitability]
reaction type: solution phase peptide synthesis | [Purification Methods]
Crystallise it from EtOH. [Kaneko J Chem Soc Jpn 60 538 1939, Rudman et al. J Am Chem Soc 74 551 1952, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2694-2697 1961, Beilstein 14 III 1187, 14 IV 1317.] |
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