| Identification | More | [Name]
N-Ethyl-2-pyrrolidone | [CAS]
2687-91-4 | [Synonyms]
1-ETHYL-2-PYRROLIDINONE
1-ETHYL-2-PYRROLIDONE
NEP
N-ETHYL-2-AZAPENTANONE
N-ETHYL-2-PYRROLIDONE
N-ETHYL-ALPHA-PYRROLIDONE
1-ethyl-2-pyrrolidinon
1-ethyl-pyrrolidin-2-one
2-Pyrrolidinone, 1-ethyl-
Agsol Ex 2
ethyl-2-pyrrolidone
N-Ethyl-2-pyrrolidinone
N-Ethylpyrrolidinone
N-Ethylpyrrolidone
1-Ethyl-2-pyrrolidinone,98%
1-Ethylpyrrolidin-2-on
N-Ethyl-a-pyrrolidone | [EINECS(EC#)]
220-250-6 | [Molecular Formula]
C6H11NO | [MDL Number]
MFCD00003199 | [Molecular Weight]
113.16 | [MOL File]
2687-91-4.mol |
| Chemical Properties | Back Directory | [Appearance]
clear liquid | [Melting point ]
87.5-88.5 °C | [Boiling point ]
97 °C/20 mmHg (lit.) | [density ]
0.992 g/mL at 25 °C(lit.)
| [vapor pressure ]
18Pa at 20℃ | [refractive index ]
n20/D 1.465(lit.)
| [Fp ]
169 °F
| [storage temp. ]
Sealed in dry,Room Temperature | [form ]
Liquid | [pka]
-0.41±0.20(Predicted) | [color ]
Clear | [PH]
8-9 (100g/l, H2O, 20℃) | [biological source]
rabbit | [explosive limit]
1.3-7.7%(V) | [Water Solubility ]
1000g/L at 23℃ | [BRN ]
107971 | [Specific Activity]
4.25-5.75nmol/min·mg | [InChIKey]
ZFPGARUNNKGOBB-UHFFFAOYSA-N | [LogP]
-0.2 at 20℃ | [CAS DataBase Reference]
2687-91-4(CAS DataBase Reference) | [NIST Chemistry Reference]
1-Ethyl-2-pyrrolidinone(2687-91-4) | [EPA Substance Registry System]
2687-91-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed.
R36:Irritating to the eyes. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
1
| [RTECS ]
UY5769250
| [Autoignition Temperature]
245°C (DIN 51794) | [TSCA ]
Yes | [HS Code ]
29337900 | [Safety Profile]
Moderately toxic by
ingestion. An eye irritant. Combustible.
When heated to decomposition it emits
toxic fumes of NOx. |
| Hazard Information | Back Directory | [Chemical Properties]
clear liquid | [Uses]
1-Ethyl-2-pyrrolidone was used to modify coir fiber (from Cocos nucifera) by photocuring. | [Application]
N-Ethyl-2-pyrrolidone is commonly used as a solvent. It has a low boiling point, which makes it suitable for use in low light and at constant pressure. It is also used as an intermediate in the preparation of polycarboxylic acid. It has been shown to be involved in both viscosity and hydrogen bonding. | [Definition]
ChEBI: 1-Ethyl-2-pyrrolidinone is a N-alkylpyrrolidine. | [General Description]
1-Ethyl-2-pyrrolidone is a transdermal absorption-enhancing compound and mechanism of its effect on multilammellar liposome of stratum corneum lipid has been studied. | [Flammability and Explosibility]
Nonflammable | [Biological Activity]
CDK7 gene is a member of the cyclin-dependent protein kinase family th at is important regulators of cell cycle progression. CDK7 forms a trimeric complex with cyclin H and MAT1which functions as a CDK-activating kinase (CAK). CDK7 is an essential component of the transcription factor TFIIH th at is involved in transcription initiation and DNA repair. CDK7 is thought to serve as a direct link between the regulation of transcription and the cell cycle. | [Side effects]
Neurotoxins - Acute Solvent Syndrome
Occupational Hepatotoxin - Secondary Hepatotoxin: Cases of possible toxic effects in an occupational setting depending on human ingestion or experimental poisoning of animals.
Reproductive toxin - A chemical that is toxic to the reproductive system, including offspring defects and damage to male or female reproductive function. Reproductive toxicity includes developmental effects. | [Toxics Screening Level]
The initial threshold screening level (ITSL) for 1-ethyl-2-pyrrolidone (CAS # 2687-91-4) is 4.9 μg/m3 based on an annual averaging time. |
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