| Identification | More | [Name]
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one | [CAS]
199327-61-2 | [Synonyms]
7-METHOXY-6-(3-MORPHOLINOPROPOXY)QUINAZOLIN-4(3H)-ONE
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one
7-Methoxy-6-(3-morpholinopropoxy)-3,4-dihydroquinazolin-4-one
7-Methoxy-6-[3-(4-morpholinyl)propoxy]-4(3H)-quinazolinone | [EINECS(EC#)]
429-400-7 | [Molecular Formula]
C16H21N3O4 | [MDL Number]
MFCD12760130 | [Molecular Weight]
319.36 | [MOL File]
199327-61-2.mol |
| Chemical Properties | Back Directory | [Melting point ]
233-236 °C | [Boiling point ]
519.5±60.0 °C(Predicted) | [density ]
1.32±0.1 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
7.10±0.10(Predicted) | [color ]
White to Off-White | [Usage]
Gefitinib intermediate | [CAS DataBase Reference]
199327-61-2(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Description]
7-Methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4(3H)-one is a pharmaceutical intermediate used in the preparation of gefitinib, an orally active selective inhibitor of the epidermal growth factor receptor tyrosine kinase, an enzyme that regulates intracellular signalling pathways that associated with the proliferation and survival of cancer cells. | [Chemical Properties]
White Solid | [Uses]
Gefitinib intermediate | [Uses]
Gefitinib intermediate. |
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