| Identification | More | [Name]
Uridine-5'-triphosphoric acid trisodium salt | [CAS]
19817-92-6 | [Synonyms]
URIDINE 5'-TRIPHOSPHATE TETRASODIUM
URIDINE-5'-TRIPHOSPHATE TETRASODIUM SALT
Uridine 5'-triphosphatetrisodium salthydrate
Uridine-5'-triphosphoric acid trisodium salt
uridine 5'-(disodium dihydrogen triphosphate)
URIDINE 5'-TRIPHOSPHATE TRISODIUM*100 MM SOLUTION M
URIDINE 5'-TRIPHOSPHATE TYPE IV*TRISODIU M
URIDINE 5'-TRIPHOSPHATE SODIUM FROM*YEAS T TYPE III
URIDINE-5'-TRIPHOSPATE (UTP) TRISODIUM SALT, ULTRA PURE GRADE 98+% (DRY BASIS)
URIDINE-5'-TRIPHOSPATE (UTP) TRISODIUM SALT, CULTURE REAGENT 98%
URIDINE-5'-TRIPHOSPATE (UTP) TRISODIUM SALT, 97%
URIDINE-5'-TRIPHOSPATE (UTP), 100MM SOLUTION
Uridine 5-(tetrahydrogen triphosphate), trisodium salt
utp na3
URIDINE-5''-TRIPHOSPHATE TRISODIUM SALT DIHYDRATE (UTP)
URIDINE-5'-TRIPHOSPHATE TRISODIUM SALT DIHYDRATE extrapure
Uridine 5μ-triphosphate hydrate trisodium salt
UTP, 100mM Solution | [EINECS(EC#)]
243-347-5 | [Molecular Formula]
C9H12N2Na3O15P3 | [MDL Number]
MFCD06200764 | [Molecular Weight]
550.09 | [MOL File]
19817-92-6.mol |
| Chemical Properties | Back Directory | [Appearance]
White crystalline powder | [Melting point ]
140 °C | [Fp ]
113 °C | [storage temp. ]
−20°C
| [solubility ]
H2O: soluble25 mg of UTP in 0.5 ml of solvent, clear, colorless | [form ]
Powder | [color ]
White | [biological source]
yeast | [Water Solubility ]
75 g/100 mL (20 ºC) | [BRN ]
3585234 | [InChIKey]
IKVGSWYKOMJBSB-RFFBCSJBNA-N | [SMILES]
O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1N1C=CC(=O)NC1=O)O.[NaH] |&1:1,2,3,19,r| | [CAS DataBase Reference]
19817-92-6(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R68/20/21/22:Harmful: possible risk of irreversible effects through inhalation, in contact with skin and if swallowed .
R68:Possible risk of irreversible effects.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S22:Do not breathe dust .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
1
| [RTECS ]
YU8083000 | [HS Code ]
29349990 |
| Hazard Information | Back Directory | [Description]
Uridine-5'-triphosphoric acid trisodium salt (19817-92-6), also known as UTP, is a polyphosphate analogue of uridine that is used in the synthesis of agonists at the G-protein-coupled P2Y receptors.
| [Chemical Properties]
White crystalline powder | [Uses]
Uridine-5'-triphosphoric acid trisodium salt (19817-92-6) is a polyphosphate analogue of the nucleoside uridine used in the preparation of potent and selective agonists at the G-protein-coupled P2Y receptors.
| [Uses]
??? | [Uses]
P2Y receptor agonist. | [Uses]
psychostimulant | [Application]
Uridine-5'-triphosphoric acid trisodium salt (19817-92-6) solution can be used to increase intracellular Ca2+ levels in rat primary tracheal epithelial cells. It is also used as a nucleotide substrate to analyze the activity of MutT homolog 1 (MTH1).
| [Biochem/physiol Actions]
Uridine-5′-Triphosphate?(UTP,19817-92-6) is a cytosolic nucleotide component of nucleic acids. It serves as a signaling molecule in the extracellular space. Uridine-5′-Triphosphate?(UTP) is involved in various pathophysiological responses in the nervous system.?UTP also plays a major role in the regeneration process.
| [in vitro]
Uridine triphosphate (UTP) (0, 10, 100, 250, 500, and 1000 μM; 2, 4, 6, 8, 10, and 12 h) trisodium salt enhances RT4-D6P2T cells migration and wound repair. Uridine triphosphate trisodium salt induces Schwannoma cell migration through the activation of P2Y2 receptors and the increase of extracellular MMP-2 activation and expression. Uridine triphosphate (UTP) trisodium salt (Uridine-5'-triphosphoric acid trisodium salt) evokes MAPK phosphorylation in a biphasic pattern MAPK phosphorylation, with an early transient phosphorylation 5 min after treatment and a late and sustained phosphorylation that appeared at 6 h and lasted up to 24 h. |
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