| Identification | Back Directory | [Name]
SR27897 | [CAS]
136381-85-6 | [Synonyms]
SR27897
SR 27897 hydrate
{2-[4-(2-Chloro-phenyl)-thiazol-2-ylcarbamoyl]-indol-1-yl}-acetic acid
2-[[[4-(2-Chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-aceticacid
1H-Indole-1-acetic acid,2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]carbonyl]-
2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-acetic acid hydrate | [Molecular Formula]
C20H14ClN3O3S | [MDL Number]
MFCD21608519 | [MOL File]
136381-85-6.mol | [Molecular Weight]
411.86 |
| Chemical Properties | Back Directory | [density ]
1.49±0.1 g/cm3(Predicted) | [storage temp. ]
Desiccate at +4°C | [solubility ]
DMSO: ≥10mg/mL at warmed to 60°C | [form ]
powder | [pka]
4.00±0.10(Predicted) | [color ]
white to tan |
| Hazard Information | Back Directory | [Uses]
SR 27897 is a human cholecystokinin type 1 (CCK1) competitive antagonist. | [Definition]
ChEBI: 2-[2-[[[4-(2-chlorophenyl)-2-thiazolyl]amino]-oxomethyl]-1-indolyl]acetic acid is an indolyl carboxylic acid. | [Biological Activity]
Potent, non-peptide CCK 1 receptor antagonist that displays > 33-fold selectivity over CCK 2 receptors (EC 50 values are 6 and 200 nM respectively). Causes an increase in plasma leptin levels and increases food intake in rats in vivo . | [storage]
Store at -20°C |
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