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ChemicalBook--->CAS DataBase List--->133180-01-5

133180-01-5

133180-01-5 Structure

133180-01-5 Structure
IdentificationMore
[Name]

Fmoc-O-trityl-L-threonine
[CAS]

133180-01-5
[Synonyms]

FMOC-L-THR(TRT)-OH
FMOC-O-TRITYL-L-THREONINE
FMOC-THR(TRT)
FMOC-THR(TRT)-OH
N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-TRITYL-L-THREONINE
N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-O-TRITYL-L-THREONINE
N-ALPHA-FMOC-O-TRITYL-L-THREONINE
TRITYL-L-THREONINE
FMOC-THR(TRT)-OH 99%
N-(9-Fluorenylmethyloxycarbonyl)-O-trityl-L-threonine
[Molecular Formula]

C38H33NO5
[MDL Number]

MFCD00237034
[Molecular Weight]

583.67
[MOL File]

133180-01-5.mol
Chemical PropertiesBack Directory
[Melting point ]

70-85°C
[Boiling point ]

753.0±60.0 °C(Predicted)
[density ]

1.241±0.06 g/cm3(Predicted)
[storage temp. ]

-20°C
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

Powder
[pka]

3.31±0.10(Predicted)
[CAS DataBase Reference]

133180-01-5(CAS DataBase Reference)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H312-H332
[Precautionary statements ]

P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501
[HS Code ]

2924297099
Hazard InformationBack Directory
[Chemical Properties]

White to off-white crystalline powder
[Uses]

peptide synthesis
[General Description]

The side-chain Trt group can be selectively removed with 1% TFA in DCM containing 5% TIS, enabling the side-chain hydroxyl group to be selectively modified whilst the derivative is attached to the solid support. This is an excellent derivative for the synthesis of phosphothreonine containing peptides and peptides modified at the threonine side-chain [1]. The use of trityl protected amino acids was shown to result in purer products than when standard t-Bu protected amino acids were utilized [2].

The product number for this product was previously 04-12-1141.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.
[reaction suitability]

reaction type: Fmoc solid-phase peptide synthesis
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