| Identification | Back Directory | [Name]
WAY 208466 dihydrochloride | [CAS]
1207064-61-6 | [Synonyms]
WAY-208466 (hydrochloride) | [Molecular Formula]
C17H19ClFN3O2S | [MDL Number]
MFCD20926423 | [MOL File]
1207064-61-6.mol | [Molecular Weight]
383.87 |
| Chemical Properties | Back Directory | [storage temp. ]
Desiccate at -20°C | [solubility ]
Soluble to 80 mM in water and to 80 mM in DMSO | [form ]
Powder | [color ]
Off-white to light yellow | [Water Solubility ]
H2O: 5mg/mL, clear (warmed) |
| Hazard Information | Back Directory | [Uses]
3-[(3-Fluorophenyl)sulfonyl]-N,N-dimethyl-1H-pyrrolo[2,3-b]pyridine-1-ethanamine Dihydrochloride is the dihydrochloride salt of 3-[(3-Fluorophenyl)sulfonyl]-N,N-dimethyl-1H-pyrrolo[2,3-b]pyridine-1-ethanamine which is a selective 5-HT6 receptor agonist. It has been proven to have antidepressant and anxiolytic effects on rats suggesting its usefulness as a potential antidepressant. | [Biological Activity]
WAY-208466 is a high affinity (Ki = 4.8 nM) 5-HT6 receptor agonist. In HeLa cells expressing cloned human 5-HT6the compound induced cAMP production (EC50 = 7.3 nM; Emax = 100%). WAY-208466 increases cortical GABA levels and exhibits anxiolytic activity in r at studies. | [storage]
Desiccate at RT |
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