| Identification | More | [Name]
Homosalate | [CAS]
118-56-9 | [Synonyms]
2-HYDROXYBENZOIC ACID 3,3,5-TRIMETHYLCYCLOHEXYL ESTER
3,3,5-TRIMETHYLCYCLOHEXYL 2-HYDROXYBENZOATE
3,3,5-TRIMETHYLCYCLOHEXYL SALICYLATE
EUSOLEX(R) HMS
HELIOPHAN
HMS
HOMOMENTHYLE SALICYLATE
HOMOMENTHYL SALICYLATE
HOMOSALATE
SALICYLIC ACID 3,3,5-TRIMETHYLCYCLOHEXYL ESTER
trimethylcyclohenyl salicylate
Benzoic acid, 2-hydroxy-, 3,3,5-trimethylcyclohexyl ester
Benzoicacid,2-hydroxy-,3,3,5-trimethylcyclohexylester
component of Coppertone
Coppertone
Filtersol ''A''
Filtrosol A
Heliopan
Homosalat
Kemester HMS | [EINECS(EC#)]
204-260-8 | [Molecular Formula]
C16H22O3 | [MDL Number]
MFCD00019377 | [Molecular Weight]
262.34 | [MOL File]
118-56-9.mol |
| Chemical Properties | Back Directory | [Definition]
A homolog of menthyl salicylate. | [Appearance]
Liquid. | [Boiling point ]
161-165°C (12 torr) | [density ]
1.05 | [vapor pressure ]
0.015Pa at 25℃ | [refractive index ]
n20 1.516 to 1.518 | [Fp ]
169 - 173℃ | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
Chloroform (Slightly), DMSO (Slightly) | [form ]
neat | [pka]
8.10±0.30(Predicted) | [color ]
Colourless | [Odor]
at 100.00?%. mild menthol | [Water Solubility ]
<0.1 g/100 mL at 26 ºC | [BRN ]
2731604 | [LogP]
6.27 at 25℃ | [Uses]
homosalate is a chemical uVB absorber included in the FDA’s Category I Sunscreen Chemical list. Its approved usage level is 4 to 15 percent by the FDA and 10 percent by the european union’s Cosmetic Directive. | [CAS DataBase Reference]
118-56-9(CAS DataBase Reference) | [NIST Chemistry Reference]
Homosalate(118-56-9) | [EPA Substance Registry System]
118-56-9(EPA Substance) |
| Hazard Information | Back Directory | [General Description]
Viscous or light yellow to slightly tan liquid or oil. | [Reactivity Profile]
An ester and a phenol. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides. | [Air & Water Reactions]
This compound will hydrolyze under basic conditions. . Insoluble in water. | [Fire Hazard]
This chemical is probably combustible. | [Description]
Homosalate is an organic compound that belongs to a class of chemicals called salicylates. Salicylates prevent direct skin exposure to the sun’s harmful rays by absorbing ultraviolet (UV) light. Homosalate specifically absorbs short-wave UVB rays, associated with DNA damage and an increased risk of skin cancer. It is a widely used chemical in sunscreens and skin care products with SPF. However, Homosalate is a potential endocrine disruptor and studies in cells suggest it may impact hormones. In addition to direct health concerns following homosalate exposure, the chemical may also enhance the absorption of pesticides in the body. | [Chemical Properties]
Liquid. | [Brand name]
Eusolex (Rona
Laboratories, Great Britain); Heliophan (Greeff). | [Flammability and Explosibility]
Nonflammable | [Side effects]
Similar to oxybenzone, homosalate affects hormone activity once absorbed. Skin rashes, acne and skin irritation are rare side effects of the toxic chemical. Estrogen, androgen and progesterone have all been found to be disrupted when the body is exposed to homosalate.
| [storage]
Store at -20°C |
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