| Identification | More | [Name]
Methyl 4-bromocrotonate | [CAS]
1117-71-1 | [Synonyms]
4-BROMOCROTONIC ACID METHYL ESTER
METHYL 4-BROMOCROTONATE
METHYL TRANS-4-BROMO-2-BUTENOATE
TRANS-4-BROMO-2-BUTENOIC ACID METHYL ESTER
TRANS-METHYL-4-BROMOCROTONATE
4-Bromo-2-butenoic acid methyl ester
4-bromo-2-butenoicacimethylester
4-bromo-crotonicacimethylester
Crotonic acid, 4-bromo-, methyl ester
Methyl (2E)-4-bromo-2-butenoate
Methyl 4-bromo-2-butenoate
Methyl bromocrotonate
Methyl gamma-bromocrotonate
methyl4-bromo-2-butenoate
methylbromocrotonate
METHYL 4-BROMOCROTONATE, TECH., 85%
Methyl 4-bromocrotonate, pract., 85%
2-Butenoic acid, 4-bromo-, methyl ester
methyl 4-bromocrotonate (4-bromocrotonic acid methyl ester)
Methyl-4-bromocrotonate(min.85%trans) | [EINECS(EC#)]
214-251-0 | [Molecular Formula]
C5H7BrO2 | [MDL Number]
MFCD00000246 | [Molecular Weight]
179.01 | [MOL File]
1117-71-1.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,C | [Risk Statements ]
R37/38:Irritating to respiratory system and skin .
R41:Risk of serious damage to eyes.
R34:Causes burns.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S39:Wear eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
3265 | [WGK Germany ]
3
| [RTECS ]
GQ3120000
| [F ]
8-9 | [Hazard Note ]
Corrosive | [TSCA ]
Yes | [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29161900 |
| Hazard Information | Back Directory | [Chemical Properties]
clear yellow liquid | [Uses]
It is a useful synthetic intermediate. It was used in the synthesis of irreversible inhibitors of EGFR and HER-2 tyrosine kinases with enhanced antitumor activities. | [Preparation]
ethyl or methyl crotonate is treated with N-Bromosuccinimide/CCl4 and Dibenzoyl Peroxide. | [storage]
handle under nitrogen and in a fume hood. Store refrigerated and tightly closed. |
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