| Identification | Back Directory | [Name]
phleomycin D1 | [CAS]
11031-11-1 | [Synonyms]
ZEOCIN
ZEOCINE
phleomycin D1
Zeocin (Phleomycin D1, zeomycin)
Bleomycinamide, N1-[4-[(aminoiminomethyl)amino]butyl]-7,8-dihydro-
(7R)-N1-[4-[[Amino(imino)methyl]amino]butyl]-7,8-dihydrobleomycinamide | [Molecular Formula]
C55 H86 N20 O21 S2 | [MOL File]
11031-11-1.mol | [Molecular Weight]
1427.52 |
| Hazard Information | Back Directory | [Uses]
Zeocin is a DNA intercalating agent and a glycopeptide antibiotic. Zeocin is a related compound of Bleomycin (B595805), a glycopeptide antibiotic. | [Definition]
ChEBI: Phleomycin D1 is a glycopeptide originally isolated from the bacterium Streptomyces verticillus which contains a (4'R)-4',5'-dihydro-2,4'-bi-1,3-thiazole-2',4-diyl moiety with a a 4-guanidylbutylaminocarbonyl group attached to the 4-position of the terminal thiazole ring. Like all phleomycins, phleomycin D1 can form complexes with redox-active metals such as Co, Cu, and Fe. It has a role as an antineoplastic agent, an antifungal agent, an antimicrobial agent, an antibacterial agent and a bacterial metabolite. It is a chelate-forming peptide, a member of guanidines, a disaccharide derivative, a bi-1,3-thiazole and a glycopeptide. |
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