| Identification | More | [Name]
1,3-Diaminopropane | [CAS]
109-76-2 | [Synonyms]
1,3-BIAMINOPROPANE
13DAP
1,3-DIAMINOPROPANE
1,3-PROPANEDIAMINE
1,3-PROPYLENE DIAMINE
AKOS BBS-00004281
RARECHEM AL BW 0043
TRIMETHYLENEDIAMINE
alpha,omega-propanediamine
H2N(CH2)3NH2
Propane-1,3-diamine
1,3-DIAMINOPROPANE, 99+%
1,3 Diaminopropan
Propanediamine, 1,3-
1,3-Proplenediamine
1,3-Propanediamine, Trimethylenediamine | [EINECS(EC#)]
203-702-7 | [Molecular Formula]
C3H10N2 | [MDL Number]
MFCD00008228 | [Molecular Weight]
74.12 | [MOL File]
109-76-2.mol |
| Chemical Properties | Back Directory | [Appearance]
colourless liquid | [Melting point ]
-12 °C | [Boiling point ]
140 °C(lit.)
| [density ]
0.888 g/mL at 25 °C(lit.)
| [vapor pressure ]
<8 mm Hg ( 20 °C)
| [refractive index ]
n20/D 1.458(lit.)
| [Fp ]
120 °F
| [storage temp. ]
Flammables area | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Liquid | [pka]
10.94(at 10℃) | [color ]
Clear | [PH]
>12 (100g/l, H2O, 20℃) | [Stability:]
Stable. Hygroscopic. Flammable-readily forms explosive mixtures with air. Incompatible with acid anhydrides, acid chlorides, acids, strong oxidizing agents. | [explosive limit]
2.8-15.2%(V) | [Water Solubility ]
SOLUBLE | [Sensitive ]
Air Sensitive | [BRN ]
605277 | [Dielectric constant]
9.6（Ambient） | [LogP]
-1.05 at 25℃ | [CAS DataBase Reference]
109-76-2(CAS DataBase Reference) | [NIST Chemistry Reference]
1,3-Propanediamine(109-76-2) | [EPA Substance Registry System]
109-76-2(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
T,C | [Risk Statements ]
R10:Flammable.
R22:Harmful if swallowed.
R24:Toxic in contact with skin.
R35:Causes severe burns. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S25:Avoid contact with eyes .
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
UN 2922 8/PG 2
| [WGK Germany ]
2
| [RTECS ]
TX6825000
| [F ]
34 | [Autoignition Temperature]
662 °F | [TSCA ]
Yes | [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
29212900 | [Safety Profile]
Poison by ingestion and
skin contact. Experimental teratogenic
effects. A severe skin and eye irritant.
Flammable liquid when exposed to heat,
sparks, or flame. When heated to
decomposition it emits toxic fumes of NOx.
See also AMINES. | [Toxicity]
LD50 orally in Rabbit: 700 mg/kg LD50 dermal Rabbit 200 mg/kg |
| Raw materials And Preparation Products | Back Directory | [Raw materials]
1,2-Dibromopropane-->1,3-Propanedicarboxamide-->N-CARBOBENZOXY-1,3-DIAMINOPROPANE HYDROCHLORIDE-->1,3-Dibromopropane-->1,3-Propanediol-->3-Aminopropionitrile-->1,3-Dichloropropane | [Preparation Products]
Homopiperazine-->Cinmethylin-->N-Boc-Ethylenediamine-->N-Boc-1,3-propanediamine-->Cocoamidopropyl betaine-->dihydroxyethyl p-octadecyl phenylsulfonyl amino propyl ammoium propylsulfonate-->Propanenitrile, 3-[(3-aminopropyl)amino]--->2,3,4,5-TETRAHYDRO-1H-BENZO[B][1,4]DIAZEPINE-->N,N'-BIS(3-AMINOPROPYL)-1,3-PROPANEDIAMINE-->2-(3,4-DIMETHYLPHENYL)PYRIDINE |
| Hazard Information | Back Directory | [General Description]
Water-white mobile liquid with an odor of amine. | [Reactivity Profile]
1,3-DIAMINOPROPANE(109-76-2) is heat sensitive. This compound may react with oxidizing agents. | [Air & Water Reactions]
Highly flammable. Water soluble. | [Health Hazard]
ACUTE/CHRONIC HAZARDS: This compound is a strong irritant to eyes and skin: corrosive HAZARDOUS DECOMPOSITION PRODUCTS. | [Fire Hazard]
This compound is a flammable liquid. | [Chemical Properties]
colourless liquid | [Uses]
1,3-Diaminopropane is commonly used in the preparation of cholinesterase inhibitors and thrombosis inhibitors. It is also used as a polymer cross linkage agent, polyurethane extender and spray coatings. It is involved in the preparation of agrochemicals and pharmaceutical intermediates. Further, it acts as a building block in the synthesis of heterocyclic compounds, which finds application in textile finishing. In addition to this, it is used as a ligand and form coordination complexes. | [Definition]
ChEBI: An alkane-alpha,omega-diamine comprising a propane skeleton with amino substituents at positions 1 and 3. | [Production Methods]
1,3-Diaminopropane is produced in a twostage continuous process, under a pressure of 10 – 20 MPa. In a first reactor, acrylonitrile reacts with excess ammonia at 70 – 100 ℃ to give 2-aminopropionitrile and bis(cyanoethyl) amine. The mixture of aminonitriles is then hydrogenated in a downstream reactor over a fixed-bed catalyst (cobalt or nickel) at 60 – 120 ℃ to give 1,3-diaminopropane and bis (aminopropyl)amine. The yield of 1,3- diaminopropane can be increased by adding a polar solvent and water or by using a large excess of ammonia.
| [Flammability and Explosibility]
Flammable |
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