(TRIETHYLSILYL)ACETYLENE synthesis
- Product Name:(TRIETHYLSILYL)ACETYLENE
- CAS Number:1777-03-3
- Molecular formula:C8H16Si
- Molecular Weight:140.3
994-30-9
430 suppliers
$12.00/5g
1066-26-8
96 suppliers
$48.00/50g
1777-03-3
213 suppliers
$16.80/1G
Yield:1777-03-3 82%
Reaction Conditions:
in tetrahydrofuran at 0; for 12 h;Inert atmosphere;Reflux;Large scale;Solvent;Temperature;
Steps:
1
Take 1kg sodium acetylene suspended in 5L of tetrahydrofuran, under nitrogen, was slowly added dropwise at 0 triethylChlorosilanes, about 4h addition was complete, the reaction was slowly warmed to reflux for 8h, cooled to room temperature, the reaction solution was added dropwise500ml of ice water to quench the reaction. The organic phase was washed with saturated brine 500ml × 3 after washing, drying, suction filtration. 10 × 150cmVacuum distillation column packing fractions were collected about 45 , the yield of about 82%.
References:
Pharmaceutical Technology Co., Ltd.;Xue, Song CN105566372, 2016, A Location in patent:Paragraph 0025; 0026
994-30-9
430 suppliers
$12.00/5g
79-01-6
478 suppliers
$17.60/100ml
1777-03-3
213 suppliers
$16.80/1G
1112-48-7
87 suppliers
$93.00/5g
4301-14-8
127 suppliers
$55.20/100ml
1777-03-3
213 suppliers
$16.80/1G
994-30-9
430 suppliers
$12.00/5g
4301-14-8
127 suppliers
$55.20/100ml
1777-03-3
213 suppliers
$16.80/1G