TERT-BUTYL 4-CYANOPHENYLCARBAMATE synthesis
- Product Name:TERT-BUTYL 4-CYANOPHENYLCARBAMATE
- CAS Number:143090-18-0
- Molecular formula:C12H14N2O2
- Molecular Weight:218.25
24424-99-5
867 suppliers
$13.50/25G
873-74-5
661 suppliers
$9.00/1g
143090-18-0
57 suppliers
$22.50/1g
Yield: 88%
Reaction Conditions:
with sulfonated reduced graphene oxide in neat (no solvent) at 20; for 3 h;
Steps:
Boc Protection of Amines; General Procedure
General procedure: To a magnetically stirred solution of (Boc)2 (1 mmol, 218.25 mg) andSrGO (7.5 mg), was added the respective amine (1 mmol) and stirredfor the appropriate time (Table 2) at RT. The progress of the reactionwas monitored by TLC. After the completion of the reaction, DCM (2mL) was added to the reaction mixture and the catalyst was separatedby vacuum filtration. The catalyst was washed with EtOH (3 × 5 mL)and subsequently dried in an air oven at 70 °C for 3 h and reused forfurther reactions. The solvent was concentrated under reduced pressureto yield N-t-Boc protected amine derivatives. The products werecharacterized by 1H NMR, 13C NMR, MS, and IR spectroscopy.
References:
Awasthi, Satish K.;Mishra, Anupam;Mittal, Rupali [Synthesis,2020,vol. 52,# 4,p. 591 - 601]
4248-19-5
378 suppliers
$5.00/5g
623-00-7
485 suppliers
$6.00/10g
143090-18-0
57 suppliers
$22.50/1g
104741-75-5
0 suppliers
inquiry
143090-18-0
57 suppliers
$22.50/1g
226065-32-3
0 suppliers
inquiry
143090-18-0
57 suppliers
$22.50/1g
623-03-0
480 suppliers
$6.00/25g
4248-19-5
378 suppliers
$5.00/5g
143090-18-0
57 suppliers
$22.50/1g