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ChemicalBook CAS DataBase List (R)-N-Acetyl-alpha-allylglycine, 98% ee
121786-40-1

(R)-N-Acetyl-alpha-allylglycine, 98% ee synthesis

8synthesis methods
50299-14-4 Synthesis
N-ACETYL-DL-ALLYLGLYCINE

50299-14-4
26 suppliers
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(R)-N-Acetyl-alpha-allylglycine, 98% ee

121786-40-1
6 suppliers
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78553-51-2 Synthesis
CBZ-ALPHA-ALLYL-L-GLY

78553-51-2
59 suppliers
$36.00/100mg

4-Pentenoic acid, 2-(acetylamino)-, (2S)-

149117-86-2
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Yield:78553-51-2 24% , 80 % ee

Reaction Conditions:

Stage #1: N-Acetyl-α-allylglycinewith thermococcus litoralis L-aminoacylase;tris hydrochloride at 70; pH=8;Resolution of racemate;Large scale;Enzymatic reaction;
Stage #2: benzyl chloroformatewith sodium hydroxide in tetrahydrofuran;water at 5 - 10; pH=7.5 - 8.5;Large scale;

References:

Lloyd, Richard C.;Smith, Mark E. B.;Brick, Dean;Taylor, Stephen J. C.;Chaplin, David A.;McCague, Raymond [Organic Process Research and Development,2002,vol. 6,# 6,p. 762 - 766]

50299-14-4 Synthesis
N-ACETYL-DL-ALLYLGLYCINE

50299-14-4
26 suppliers
inquiry

16338-48-0 Synthesis
L-Allylglycine

16338-48-0
255 suppliers
$11.00/250mg

(R)-N-Acetyl-alpha-allylglycine, 98% ee

121786-40-1
6 suppliers
inquiry