N,N-Dibutyl-1,3-propanediamine synthesis
- Product Name:N,N-Dibutyl-1,3-propanediamine
- CAS Number:1187-33-3
- Molecular formula:C11H23NO
- Molecular Weight:185.31
Yield:1187-33-3 90%
Reaction Conditions:
with sodium hydroxide in water;toluene at 20; for 0.5 h;Cooling with ice;
Steps:
1
Ν,Ν-dibutyl-propionamide (hereinafter dibutylpropionamide) was synthesized in a two- phase system composed of 25 wt% NaOH aqueous solution (625 g), toluene (160 ml) and dibutylamine (342 g). To that ice-cooled mixture, propionic acid chloride (189 g) was added drop wise. After the addition, the reaction mixture was stirred 30 minutes at room temperature. The two phases were separated. The organic phase was fractional distillated under vaccum to obtain the purified product (335 g, 90% yield).
References:
WO2015/67524,2015,A1 Location in patent:Page/Page column 21
802294-64-0
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