Myristoyl chloride synthesis
- Product Name:Myristoyl chloride
- CAS Number:112-64-1
- Molecular formula:C14H27ClO
- Molecular Weight:246.82
544-63-8
614 suppliers
$5.00/5g
112-64-1
206 suppliers
$29.12/25G
Yield:112-64-1 98.1%
Reaction Conditions:
with thionyl chloride in N,N-dimethyl-formamide at -5 - 70; for 4.33333 h;
Steps:
2
Under ice bath -5 ° C,1 g of myristic acid (4.38 mmol)Dissolved in 5ml of freshly steamed thionyl chloride,Add 2 drops of DMF,Stir at room temperature for 20 minutes.Warming to 70 ° C, reaction for 4 h,Vacuum distillation,Distilled off thionyl chloride and other low boiling impurities,Collecting target fractions,Obtained 1.06 g of myristoyl chloride,Colorless oily liquid with a content of 98.8%,The yield was 98.1%.
References:
North China Pharmaceutical Group Drug Discovery Co., Ltd.;Dong Guimin;Liu Wei;Hu Junping;Qiu Zhaolai;Fu Ankun;An Liya CN109867600, 2019, A Location in patent:Paragraph 0028
822-12-8
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$13.00/5g
112-64-1
206 suppliers
$29.12/25G
79-37-8
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$17.67/10gm:
544-63-8
614 suppliers
$5.00/5g
112-64-1
206 suppliers
$29.12/25G