Julolidine synthesis
- Product Name:Julolidine
- CAS Number:479-59-4
- Molecular formula:C12H15N
- Molecular Weight:173.25
62-53-3
504-63-2
479-59-4
The general procedure for the synthesis of julolidine from aniline and 1,3-propanediol was as follows: aniline (1.0 mmol), IrCl3-3H2O (5.0 mol%, based on the amount of 1,3-propanediol), and rac-BINAP (7.5 mol%) were added to a reaction vial in air. Subsequently, homotrimethylbenzene (0.5 mL) and 1,3-propanediol (1.3 mmol) were added to the reaction vial and the reaction was stirred for 18 hours at 165 °C. After completion of the reaction, the reaction mixture was diluted with hexane and then filtered through filter paper. The filtrate was concentrated under vacuum and the resulting residue was purified by fast column chromatography on SiO2 (eluent ratio tBuOMe:hexane=1:15) to give 2,3,6,7-tetrahydro-1H,5H-benzo[ij]quinolizine as the final product.
31121-11-6
45 suppliers
$16.00/250mg
479-59-4
147 suppliers
$23.30/1g
62-53-3
688 suppliers
$10.00/1g
31121-11-6
45 suppliers
$16.00/250mg
106-49-0
409 suppliers
$5.00/5 g
479-59-4
147 suppliers
$23.30/1g
![1H,5H-Benzo[ij]quinolizine, 2,3,6,7-tetrahydro-9-methoxy-](/CAS/20200611/GIF/6403-55-0.gif)
6403-55-0
1 suppliers
inquiry