天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List Fmoc-N-methyl-L-leucine
103478-62-2

Fmoc-N-methyl-L-leucine synthesis

4synthesis methods
-

Yield:-

Reaction Conditions:

with toluene-4-sulfonic acid in toluene; for 0.5 h;Reflux;Dean-Stark;

Steps:

4.2.1. Step-1 Synthesis of Oxazolidinones from Fmoc Leu

General procedure: The Fmoc Leu (5 mmol), paraformaldehyde (6.66 eq., 1 g) and p-toluenesulphonic acid (0.12 eq.,100 mg) were suspended in toluene (100 mL) in 250 mL three neck RBF. The mixture was refluxed for30 min in a Dean-Stark setup and reaction was monitored by TLC (97.5:2:0.5 CHCl3:MeOH:AcOH).The solution was cooled, washed with saturated NaHCO3 and dried over anhydrous NaSO4.Concentration in vacuo gave the crude product which in most cases solidified upon standing. In somecases, purification via flash chromatography was required (silica gel, 3:7 ethylacetate:pentane).

References:

Lunagariya, Jignesh;Zhong, Shenghui;Chen, Jianwei;Bai, Defa;Bhadja, Poonam;Long, Weili;Liao, Xiaojian;Tang, Xiaoli;Xu, Shihai [Marine Drugs,2016,vol. 14,# 9,art. no. 161]

Fmoc-N-methyl-L-leucine Related Search: