ChemicalBook CAS DataBase List 9-(3-bromophenyl)carbazole

9-(3-bromophenyl)carbazole synthesis

8synthesis methods

Product Name:9-(3-bromophenyl)carbazole
CAS Number:185112-61-2
Molecular formula:C18H12BrN
Molecular Weight:322.2

1-bromo-3-iodobenzene, 2.02 mL (15.8mmol), copper (Cu) 2.29 g (36.0 mmol) of calcium carbonate and 4.98 g (36.0 mmol) of DMF in 30 mL insert heated at 130 It was stirred. After the completion of the reaction, it cooled to ambient temperature, diluted with ethyl acetate to a vacuum filter, and passed through a silica gel. The filtrate was concentrated under reduced pressure. Separating the product by silica gel column chromatography (ethyl acetate: n-hexane = 1: 20) to give 9-(3-bromophenyl)carbazole 3.80 g (98 per cent yield).

591-18-4 Synthesis

591-18-4
398 suppliers
$5.00/5g

86-74-8 Synthesis

86-74-8
345 suppliers
$10.00/5g

185112-61-2
205 suppliers
$7.00/250mg

Yield:185112-61-2 98%

Reaction Conditions:

with copper;potassium carbonate in N,N-dimethyl-formamide at 130;

Steps:

1.3 Synthesis of intermediate product (C)

Carbazole 2.00 g (12.0 mmol), 1-bromo-3-iodobenzene, 2.02 mL (15.8mmol), copper (Cu) 2.29 g (36.0 mmol) of calcium carbonate and 4.98 g (36.0 mmol) of DMF in 30 mL insert heated at 130 It was stirred. After the completion of the reaction, it cooled to ambient temperature and diluted with ethyl acetate to a vacuum filter, and passed through a silica gelThe filtrate was concentrated under reduced pressure. Separating the product by silica gel column chromatography (ethyl acetate: n- hexane = 1: 20) to give the desired intermediate compound (C) 3.80 g (98% yield).

References:

KR101593182,2016,B1 Location in patent:Paragraph 0427; 0430; 0438; 0439