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863578-50-1

METHYL 3-CYCLOHEXYL-2-(2-HYDROXYPHENYL)-1H-INDOLE-6-CARBOXYLATE synthesis

5synthesis methods
Benzoic acid, 4-[1-cyclohexyl-2-(2-hydroxyphenyl)-2-oxoethyl]-3-nitro-, methyl ester

1414926-67-2
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METHYL 3-CYCLOHEXYL-2-(2-HYDROXYPHENYL)-1H-INDOLE-6-CARBOXYLATE

863578-50-1
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Yield:863578-50-1 74%

Reaction Conditions:

with palladium on carbon;acetic acid in tetrahydrofuran at 60; under 1725.17 Torr;Large scale;

References:

Alorati, Anthony D.;Gibb, Andrew D.;Mullens, Peter R.;Stewart, Gavin W. [Organic Process Research and Development,2012,vol. 16,# 12,p. 1947 - 1952]