天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Welcome to chemicalbook!
Chinese English Japanese Germany Korea
010-86108875
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook CAS DataBase List 5-BROMO-2-HYDROXYBENZONITRILE
40530-18-5

5-BROMO-2-HYDROXYBENZONITRILE synthesis

11synthesis methods
-

Yield:40530-18-5 95%

Reaction Conditions:

with formic acid;hydroxylamine hydrochloride;sodium formate at 100; for 7 h;

Steps:

1

5-Bromo-2-hydroxybenzonitrile; To a solution of 5-bromosalicylaldehyde (80.0 g, 0.40 mol) in formic acid were added hydroxylamine hydrochloride (36.0 g, 0.52 mol) and sodium format (37.0 g, 0.52 mol) followed by stirring at 100°C for 7 hours. Ethyl acetate was added to the residue prepared by evaporation of the solvent, the mixture was washed with water and then an organic layer was dried. Petroleum ether was added to the residue prepared by evaporation of the solvent and the crystals separated out therefrom were filtered to give the title compound (75.2 g, 95%). 1H-NMR (DMSO-d6) δ: 6.98 (d, J=8.9 Hz, 1H), 7.65 (dd, J=8.9, 2.4 Hz, 1H), 7.86 (d, J=2.4 Hz, 1H), 11.41 (s, 1H).

References:

EP2128136,2009,A1 Location in patent:Page/Page column 7

5-BROMO-2-HYDROXYBENZONITRILE Related Search: