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ChemicalBook CAS DataBase List 5-[1-(2,3-DiMethylphenyl)ethenyl]iMidazole
1021949-47-2

5-[1-(2,3-DiMethylphenyl)ethenyl]iMidazole synthesis

6synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: magnesium; iodine / tetrahydrofuran / 35 - 65 °C / Inert atmosphere
1.2: 6 h / 20 - 25 °C
2.1: Dess-Martin periodane; magnesium sulfate / dichloromethane / 12 h / 20 - 30 °C
3.1: potassium tert-butylate / tetrahydrofuran / 18 h / 20 - 25 °C

References:

Jiangsu Zhengda Qingjiang Pharmaceutical Co., Ltd.;Meng Fanke;Chong Qinglei;Li Mingfeng;Li Xianzhe;Li Zhiming CN107857731, 2018, A

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