4'-(Octyloxy)-4-biphenylcarbonitrile synthesis
- Product Name:4'-(Octyloxy)-4-biphenylcarbonitrile
- CAS Number:52364-73-5
- Molecular formula:C21H25NO
- Molecular Weight:307.43
111-83-1
19812-93-2
52364-73-5
GENERAL STEPS: 4'-hydroxybiphenyl-4-carbonitrile (20.0 g, 0.1 mol), potassium carbonate (28.0 g, 0.2 mol) and N,N-dimethylformamide (600 mL) were added sequentially in a 1000 mL three-necked flask with magnetic stirring turned on. Subsequently, 1-bromooctane (23.0 g, 0.12 mol) was slowly added dropwise, and the reaction system was warmed to 120 °C and kept for 48 hours. Upon completion of the reaction, the mixture was cooled to room temperature, slowly poured into ice water (1000 mL) and allowed to stand overnight. The precipitated solid product was collected by filtration and purified by recrystallization with ethanol to afford the target compound 4'-octyloxy-[1,1'-biphenyl]-4-carbonitrile.
104-92-7
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52364-73-5
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Yield:-
Steps:
Multi-step reaction with 3 steps
2: 80 percent / AlI3 / acetonitrile / 5 h / Heating
3: 85 percent / K2CO3 / acetone / 6 h / Heating
References:
Heinrich, B.;Guillon, D. [Molecular Crystals and Liquid Crystals Science and Technology, Section A: Molecular Crystals and Liquid Crystals,1995,vol. 268,p. 21 - 44]
111-83-1
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19812-93-2
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52364-73-5
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$6.00/250mg
31835-63-9
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52364-73-5
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4854-84-6
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52364-73-5
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$6.00/250mg
![4'-CYANO[1,1'-BIPHENYL]-4-YL ACETATE](/StructureFile/ChemBookStructure4/GIF/CB9447080.gif)
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52364-73-5
155 suppliers
$6.00/250mg