4-Morpholinopiperidine synthesis
- Product Name:4-Morpholinopiperidine
- CAS Number:53617-35-9
- Molecular formula:C9H18N2O
- Molecular Weight:170.25
415967-79-2
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Yield:53617-35-9 100%
Reaction Conditions:
with palladium on activated charcoal;hydrogen in isopropyl alcohol at 80; under 3750.38 Torr; for 7 h;Autoclave;Reagent/catalyst;
Steps:
11 Example 11
The compound (3) (120 g; 0.46 mol), 2-propanol (276 g), and the palladium/carbon catalyst (0.3 g in terms of metallic palladium) were placed in an autoclave with a capacity of 1 L, and then the whole was stirred at 80° C., under a hydrogen pressure of 0.5 MPa for 7 hours. After cooling the reaction, the catalyst was filtered and washed with 2-propanol to obtain a filtrate. The resulting filtrate was analyzed by gas chromatography. As a result, the yield of the compound (4) analyzed by the internal standard method was 97%, and the area percentage (excluding the solvent and the compounds with low boiling points) of the compound (4) was 100% (Table 2).
References:
US2019/210968,2019,A1 Location in patent:Paragraph 0093
334942-09-5
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53617-35-9
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2767-91-1
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![Benzonitrile, 4-[4-(4-morpholinyl)-1-piperidinyl]-](/CAS/20210305/GIF/186650-77-1.gif)
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1194-02-1
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53617-35-9
249 suppliers
$10.00/1g