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24243-38-7

2-(morpholin-4-yl)ethyl(4E)-6-(4,6-dihydroxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoate synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: O-methyltransferase / aq. phosphate buffer; glycerol / 45 °C / pH 8 / Enzymatic reaction
2: boron tribromide / dichloromethane
3: O-methyltransferase / aq. phosphate buffer; glycerol / 45 °C / pH 8 / Enzymatic reaction

References:

Zhang, Wei;Cao, Shaona;Qiu, Li;Qi, Fengxia;Li, Zhong;Yang, Ying;Huang, Shaohua;Bai, Fali;Liu, Changning;Wan, Xiaobo;Li, Shengying [ChemBioChem,2015,vol. 16,# 4,p. 565 - 569]

2-(morpholin-4-yl)ethyl(4E)-6-(4,6-dihydroxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoate Related Search: