5-Bromo-2-fluoropyridine synthesis
- Product Name:5-Bromo-2-fluoropyridine
- CAS Number:766-11-0
- Molecular formula:C5H3BrFN
- Molecular Weight:175.99
403-45-2
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$4.00/1g
766-11-0
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$6.00/5g
Yield:766-11-0 1.73 g (63%)
Reaction Conditions:
with bromine;mercury(II) oxide in tetrachloromethane;hexane;
Steps:
1.A A.
A. 2-Fluoro-5-bromopyridine A suspension of 2.2 g (15.6 mmol) of 2-fluoro-5-pyridine-carboxylic acid, 5.1 g of HgO (red) and 1.2 ml of bromine in 100 ml of CCl4 was irradiated (by) under reflux for 5 h, cooled to room temperature, filtered through celite, and the filtrate was concentrated in vacuo. The residue was dissolved in hexane, filtered, and the filtrate was concentrated in vacuo to afford 1.73 g (63%) of 2-fluoro-5-bromopyridine, as a pale yellow oil.
References:
US5618821,1997,A
39856-50-3
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$6.00/5g
766-11-0
455 suppliers
$6.00/5g
53939-30-3
475 suppliers
$5.00/1g
766-11-0
455 suppliers
$6.00/5g
624-28-2
729 suppliers
$5.00/5g
766-11-0
455 suppliers
$6.00/5g
223463-13-6
381 suppliers
$5.00/1g
766-11-0
455 suppliers
$6.00/5g