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17849-62-6

2-CHLORO-3-PHENYLPROPIONITRILE synthesis

8synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: potassium carbonate / diethyl ether / 20 °C / Inert atmosphere
2: hydrogenchloride / water / 2 h / 20 °C / Inert atmosphere
3: 1,3,5-trichloro-2,4,6-triazine / N,N-dimethyl-formamide; dichloromethane / 24 h / 20 °C / Inert atmosphere

References:

Kadunce, Nathaniel T.;Reisman, Sarah E. [Journal of the American Chemical Society,2015,vol. 137,# 33,p. 10480 - 10483]