2,6-DIMETHYLBENZOQUINONE 4-OXIME synthesis
- Product Name:2,6-DIMETHYLBENZOQUINONE 4-OXIME
- CAS Number:4965-29-1
- Molecular formula:C8H9NO2
- Molecular Weight:151.16
527-61-7
136 suppliers
$37.70/1g
4965-29-1
26 suppliers
$45.00/50mg
Yield:4965-29-1 85%
Reaction Conditions:
with hydroxylamine hydrochloride;sodium acetate in ethanol; for 1.5 h;Reflux;
Steps:
5.3. General procedure for the oximation of the parabenzoquinones13
General procedure: NH2OH*HCl (0.221 g, 3.18 mmol) and NaOAc (0.169 g,2.08 mmol) were added to a solution of the para-benzoquinone (1.22 mmol) in EtOH (11.7 mL), and the resulting mixture was refluxed for 1.5 h. The solvent was evaporated under reduced pressure and the solid residue was diluted in water (50 mL), and extracted with a mixture of ethyl acetate and ethyl ether (1:1,320 mL). The organic phase was washed with a saturated solutionof NaHCO3 (320 mL) and brine (320 mL), dried over anhydrous Na2SO4 and the solvent was evaporated under reduced pressure. The solid residue was washed with hexane (420 mL) to eliminate soluble impurities.
References:
Uliana, Marciana P.;Servilha, Bruno M.;Alexopoulos, Olga;De Oliveira, Kleber T.;Tormena, Cláudio F.;Ferreira, Marco A.B.;Brocksom, Timothy J. [Tetrahedron,2014,vol. 70,# 39,p. 6963 - 6973]
576-26-1
343 suppliers
$10.00/25g
4965-29-1
26 suppliers
$45.00/50mg
87-62-7
466 suppliers
$10.00/5G
4965-29-1
26 suppliers
$45.00/50mg
108-68-9
343 suppliers
$9.00/5g
4965-29-1
26 suppliers
$45.00/50mg