2,6-DICHLORO-4-(TRIFLUOROMETHYL)NICOTINAMIDE synthesis
- Product Name:2,6-DICHLORO-4-(TRIFLUOROMETHYL)NICOTINAMIDE
- CAS Number:158063-67-3
- Molecular formula:C7H3Cl2F3N2O
- Molecular Weight:259.01
13600-42-5
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$9.00/250mg
158063-67-3
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$35.00/250mg
Yield: 90.09%
Reaction Conditions:
with sulfuric acid at 100; for 1 h;
Steps:
1.3 (3) Preparation of 2,6-dichloro-4-(trifluoromethyl)nicotinamide
500 mL round bottom flask, 79.6 g (330 mmo 1) of 2,6-dichloro-3-cyano-4-(trifluoromethyl)pyridine concentrated sulfuric acid 400 grams heated to 100 degrees with stirring l h, after the reaction was added to the water to precipitate a solid, filtered and washed, dried to give a white solid 77 grams, yield 90.09%.
References:
Hebei Lan Tai Chemical Technology Co., Ltd.;Guo Ming;Meng Shuiqiang;Tian Penghui;Hou Jianjun CN107382848, 2017, A Location in patent:Paragraph 0043; 0048-0049
3335-46-4
103 suppliers
$9.00/1g
158063-67-3
83 suppliers
$35.00/250mg