2,5-Dichlorobenzoic acid synthesis
- Product Name:2,5-Dichlorobenzoic acid
- CAS Number:50-79-3
- Molecular formula:C7H4Cl2O2
- Molecular Weight:191.01
3032-32-4
95 suppliers
$36.00/250mg
50-79-3
332 suppliers
$7.00/5g
Yield:50-79-3 97%
Reaction Conditions:
with cobalt(II) naphthenate;Diisobutyl adipate at 78; for 2 h;Temperature;
Steps:
3
2 mol of 2,5-dichloro-6-aminobenzoic acid was added to the reaction vessel.5mol mass fraction of 76% diisobutyl adipate solution, raise the solution temperature to 78 ° C, control the stirring speed of 160 rpm, add 4 mol of cobalt naphthenate in 5 times, each time interval is 40 min, continue the reaction for 120 min Add 1200ml of 22% potassium chloride solution, layer the solution, lower the temperature of the solution to 15 °C, and adjust the pH to 5 by adding 25% oxalic acid solution.Washing with 18% potassium sulfate solution, washing with 85% by mass of methyl tert-butyl ether solution, 96% 2-methyl groupWashing with a hydrogen furan solution, distilling under reduced pressure at 20 kPa, collecting fractions at 120 ° C,The dehydrating agent was dehydrated to obtain 370.54 g of the finished 2,5-dichlorobenzoic acid, and the yield was 97%.
References:
CN108238900,2018,A Location in patent:Paragraph 0006; 0009-0014
19398-61-9
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$10.00/5G
50-79-3
332 suppliers
$7.00/5g
2476-37-1
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$8.00/10g
50-79-3
332 suppliers
$7.00/5g
21663-61-6
232 suppliers
$12.00/5g
50-79-3
332 suppliers
$7.00/5g