N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine synthesis
- Product Name:N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
- CAS Number:152460-10-1
- Molecular formula:C16H15N5
- Molecular Weight:277.32
152460-09-8
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$11.00/10g
152460-10-1
520 suppliers
$21.00/5g
Yield:152460-10-1 100%
Reaction Conditions:
with hydrazine hydrate in N,N-dimethyl-formamide at 100; for 3 h;Green chemistry;
Steps:
Synthesis of amines; general procedure
General procedure: A mixture of the organic nitro compound (1.0 mmol), NH2NH2·H2O (2.5 equiv.) and H2O2-treated AC powder (50 wt%) in DMF (1.5 mL) was stirred vigorously magnetically at 100 °C. The reaction was monitored by LC-MS or GC-MS. On completion the reaction mixture was filtered to remove the catalyst. The combined organic mixture material was dried using anhydrous Na2SO4 and filtered. The solvent was removed under reduced pressure to obtain the products. All the compounds were known and characterised by their 1H NMR and MS spectra and comparison with literature data.
References:
Jiang, Yuqin;Suo, Huajun;Zhang, Dandan;Li, Xiyong;Sun, Yamin;Ren, Baoqi;Zhang, Weiwei;Xu, Guiqing [Journal of Chemical Research,2017,vol. 41,# 9,p. 509 - 512]
7745-93-9
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$5.00/5g
66521-66-2
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$13.00/250mg
152460-10-1
520 suppliers
$21.00/5g
1016637-24-3
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152460-10-1
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350-03-8
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$10.00/5g
152460-10-1
520 suppliers
$21.00/5g
66521-66-2
200 suppliers
$13.00/250mg
152460-10-1
520 suppliers
$21.00/5g