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55037-81-5

1-(2-METHOXYBENZYL) PIPERAZINE synthesis

1synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: sodium tris(acetoxy)borohydride / dichloromethane; 1,2-dichloro-ethane / 20 h / 20 °C
2: hydrogenchloride; water / 1,4-dioxane; dichloromethane / 5 h / 20 °C

References:

Hoveyda, Hamid R.;Roy, Marie-Odile;Blanc, Sebastien;No?l, Sophie;Salvino, Joseph M.;Ator, Mark A.;Fraser, Graeme [Bioorganic and Medicinal Chemistry Letters,2011,vol. 21,# 7,p. 1991 - 1996]

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