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ChemicalBook >> CAS DataBase List >> Irinotecan

Irinotecan

Irinotecan price.
  • $29 - $1400
  • Product name: Irinotecan
  • CAS: 97682-44-5
  • MF: C33H38N4O6
  • MW: 586.68
  • EINECS:691-567-9
  • MDL Number:MFCD01862255
  • Synonyms:1,4'-Bipiperidine-1'-carboxylic acid (S)-4,11-diethyl-3,4,12,14- tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester;DQ-2805;(4S)-4,11-Diethyl-4-hydroxy-9-[[(4-piperidinopiperidino)carbonyl]oxy]-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione;SN-38-11;[1,4'-Bipiperidine]-1'-carboxylic acid, 4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester, (S)-;1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline, [1,4'-bipiperidine]-1'-carboxylic acid deriv.;Irinotecan base;(4S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl-[1,4'-bipiperidine]-1'-carboxylic acid
38 prices
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  • AHH
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biosynth Carbosynth
  • ChemScene
  • Chemtos
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Tocris
  • TRC
  • Usbiological
Package
  • 10mg
  • 10
  • 25mg
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  • 10g
  • 50
  • 50mg
  • 100mg
  • 250mg
  • 10mM(in 1mL DMSO)
  • 500MG
  • 1g
  • 5g
  • ManufacturerAHH
  • Product numberMT-52855
  • Product descriptionIrinotecan 98%
  • Packaging1g
  • Price$1030
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ51700
  • Product descriptionIrinotecan
  • Packaging100mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164809
  • Product description(S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylate 98+%
  • Packaging50mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164809
  • Product description(S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylate 98+%
  • Packaging100mg
  • Price$37
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164809
  • Product description(S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylate 98+%
  • Packaging250mg
  • Price$74
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164809
  • Product description(S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylate 98+%
  • Packaging1g
  • Price$181
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA164809
  • Product description(S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylate 98+%
  • Packaging5g
  • Price$637
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007569
  • Product descriptionIRINOTECAN 95.00%
  • Packaging500MG
  • Price$885.31
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0007569
  • Product descriptionIRINOTECAN 95.00%
  • Packaging1G
  • Price$1152.11
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5133
  • Product descriptionIrinotecan
  • Packaging100mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA5133
  • Product descriptionIrinotecan
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS023172
  • Product description(S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylate ≥98%
  • Packaging100mg
  • Price$37
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSY105303
  • Product descriptionIrinotecan ≥98%
  • Packaging10mg
  • Price$63.82
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS023172
  • Product description(S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylate ≥98%
  • Packaging250mg
  • Price$73
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS023172
  • Product description(S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylate ≥98%
  • Packaging1g
  • Price$179
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS023172
  • Product description(S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylate ≥98%
  • Packaging5g
  • Price$631
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-52855 Irinotecan 98% 1g $1030 2021-12-16 Buy
AK Scientific J51700 Irinotecan 100mg $59 2021-12-16 Buy
Ambeed A164809 (S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylate 98+% 50mg $29 2021-12-16 Buy
Ambeed A164809 (S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylate 98+% 100mg $37 2021-12-16 Buy
Ambeed A164809 (S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylate 98+% 250mg $74 2021-12-16 Buy
Ambeed A164809 (S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylate 98+% 1g $181 2021-12-16 Buy
Ambeed A164809 (S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylate 98+% 5g $637 2021-12-16 Buy
American Custom Chemicals Corporation API0007569 IRINOTECAN 95.00% 500MG $885.31 2021-12-16 Buy
American Custom Chemicals Corporation API0007569 IRINOTECAN 95.00% 1G $1152.11 2021-12-16 Buy
ApexBio Technology A5133 Irinotecan 100mg $50 2021-12-16 Buy
ApexBio Technology A5133 Irinotecan 10mM(in 1mL DMSO) $55 2021-12-16 Buy
Arctom AS023172 (S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylate ≥98% 100mg $37 2021-12-16 Buy
Arctom SY105303 Irinotecan ≥98% 10mg $63.82 2021-12-16 Buy
Arctom AS023172 (S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylate ≥98% 250mg $73 2021-12-16 Buy
Arctom AS023172 (S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylate ≥98% 1g $179 2021-12-16 Buy
Arctom AS023172 (S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylate ≥98% 5g $631 2021-12-16 Buy

Properties

Melting point :222-223°
Boiling point :873.4±65.0 °C(Predicted)
Density :1.40±0.1 g/cm3(Predicted)
storage temp. :Sealed in dry,2-8°C
solubility :Acetonitrile (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly)
form :Solid
pka :11.20±0.20(Predicted)
color :White to Brown
CAS DataBase Reference :97682-44-5(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H361 Suspected of damaging fertility or the unborn child Reproductive toxicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P281 Use personal protective equipment as required.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.
P310 Immediately call a POISON CENTER or doctor/physician.
P314 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Irinotecan is a topoisomerase I inhibitor for LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively

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