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     Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse brain tissue, Mouse kidney tissue lysates, Primary antibody: P10342(KRCC1 Antibody) at dilution 1/1350, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P10342(KRCC1 Antibody) at dilution 1/95. (Original magnification: ×200)    

  
  

**Background of KRCC1 Antibody**

KRCC1 (Lysine-Rich Coiled-Coil 1) is a protein encoded by the *KRCC1* gene, which is conserved across eukaryotes and characterized by its lysine-rich domain and coiled-coil structural motifs. These features suggest roles in protein-protein interactions and subcellular organization. KRCC1 is implicated in diverse cellular processes, including RNA metabolism, chromatin remodeling, and cell cycle regulation. Studies link it to the maintenance of genomic stability, potentially through interactions with components of the DNA damage response pathway or RNA-processing machinery.

The KRCC1 antibody is a valuable tool for detecting and analyzing KRCC1 expression and localization in various experimental models. It is commonly used in techniques like Western blotting, immunofluorescence, and immunoprecipitation to study KRCC1's distribution (nuclear/cytoplasmic), expression levels under different conditions (e.g., stress, cell cycle phases), and its association with molecular complexes. Researchers have employed this antibody to explore KRCC1's functional relevance in diseases such as cancer, where dysregulation of genomic stability pathways is common. Validation of the antibody typically includes knockout controls or siRNA-based depletion to confirm specificity. Understanding KRCC1's roles through antibody-based assays contributes to insights into its biological significance and potential therapeutic targets.