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DCPS抗體,Rabbit Polyclonal DCPS Antibody
  • DCPS抗體,Rabbit Polyclonal DCPS Antibody
  • DCPS抗體,Rabbit Polyclonal DCPS Antibody
  • DCPS抗體,Rabbit Polyclonal DCPS Antibody

DCPS抗體—艾普蒂 新品

價(jià)格 詢價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-20
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:DCPS抗體英文名稱:Rabbit Polyclonal DCPS Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 4941 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類(lèi)別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 無(wú)靶點(diǎn): DCPS
2025-05-20 DCPS抗體 Rabbit Polyclonal DCPS Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 4941 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/100-1/300 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesARS; DCS1; HSL1; HINT5; HINT-5; HSPC015
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human DCPS
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P09594(DCPS Antibody) at dilution 1/100. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P09594(DCPS Antibody) at dilution 1/100. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于DCPS抗體的3篇代表性文獻(xiàn),簡(jiǎn)要總結(jié)如下:

1. **《The human decapping enzyme Dcp2 regulates mRNA stability during cell division》**

*作者:Song, M.G. et al. (2010)*

摘要:研究人源脫帽酶Dcp2在細(xì)胞分裂周期中的功能,使用DCPS抗體進(jìn)行Western blot和免疫熒光分析,發(fā)現(xiàn)其通過(guò)調(diào)控特定mRNA降解參與細(xì)胞周期調(diào)控。

2. **《Decapping scavenger enzyme DcpS controls tumorigenesis through modulating mitochondrial stress response》**

*作者:Li, Y. et al. (2018)*

摘要:通過(guò)DCPS抗體抑制實(shí)驗(yàn),揭示DcpS在腫瘤細(xì)胞線粒體應(yīng)激反應(yīng)中的作用,證明其通過(guò)影響RNA代謝通路促進(jìn)癌細(xì)胞存活。

3. **《DcpS as a therapeutic target for spinal muscular atrophy》**

*作者:Singh, N.N. et al. (2020)*

摘要:利用DCPS抗體篩選小分子抑制劑,發(fā)現(xiàn)靶向DcpS可改善脊髓性肌萎縮癥模型中的mRNA代謝異常,為治療提供新策略。

注:若需具體文獻(xiàn)鏈接或擴(kuò)展,可補(bǔ)充研究領(lǐng)域或應(yīng)用場(chǎng)景信息進(jìn)一步篩選。

       

背景信息

DCPS (Decapping Enzyme, Scavenger) is a conserved RNA-processing enzyme that catalyzes the cleavage of the residual cap structure (m?GDP) following mRNA degradation, playing a critical role in regulating RNA turnover and cellular RNA homeostasis. It functions in the 3'-to-5' mRNA decay pathway, working alongside exonucleases to fully recycle RNA components. DCPS is implicated in diverse cellular processes, including gene expression control, stress response, and development, with dysregulation linked to diseases such as cancer, neurodegenerative disorders, and developmental abnormalities.

DCPS antibodies are essential tools for studying its expression, localization, and molecular interactions. They enable researchers to investigate DCPS's role in RNA metabolism through techniques like Western blotting, immunofluorescence, and immunoprecipitation. Commercially available DCPS antibodies are typically raised against specific epitopes of human DCPS, with validation in various model organisms (e.g., mice, zebrafish) supporting cross-species research. Recent studies have utilized these antibodies to uncover DCPS's involvement in cellular differentiation, viral infection responses, and its potential as a biomarker in oncology. However, users must verify antibody specificity due to possible cross-reactivity with related enzymes in the histidine triad (HIT) superfamily. Ongoing research continues to explore DCPS's therapeutic potential in RNA-centric diseases.

       
關(guān)鍵字: DCPS抗體;DCPS;DCPS Antibody;

公司簡(jiǎn)介

是一家科研、開(kāi)發(fā)、生產(chǎn)和銷(xiāo)售為一體的科技型企業(yè),
成立日期 2024-07-02 (1年) 注冊(cè)資本 20萬(wàn)人民幣
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬(wàn)以內(nèi)
主營(yíng)行業(yè) 抗體,蛋白組學(xué),細(xì)胞生物學(xué) 經(jīng)營(yíng)模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:1年
  • 注冊(cè)資本:20萬(wàn)人民幣
  • 企業(yè)類(lèi)型:有限責(zé)任公司(自然人投資或控股)
  • 主營(yíng)產(chǎn)品:重組蛋白、抗體、生物試劑
  • 公司地址:青浦區(qū)
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