Product Name：Dulaglutide
CAS No.：923950-08-7
Synonyms：Dulaglutide - solution in PBS；杜拉魯肽
Catalog No.：Typeptide Biotech（肽研生物）
Brand：HongTide（上海鴻肽生物）
Description：Dulaglutide是新型長(zhǎng)效GLP-1R激動(dòng)劑多肽，序列中包含31個(gè)氨基酸，由兩個(gè)具有DPP-4 抑制作用的GLP-1類似物和人免疫球蛋白重鏈IgG4-Fc 片段融合得到，在臨床表現(xiàn)中其活性與內(nèi)源性GLP-1相似，半衰期為5天，能有效延緩腎臟的清除作用。FDA于2014 年9 月批準(zhǔn)杜拉魯肽皮下注射液上市。歐盟委員會(huì)于2014年12月批準(zhǔn)杜拉魯肽皮下注射液在歐洲上市。
Dulaglutide is a novel long-acting GLP-1R agonist peptide with a sequence containing 31 amino acids. It is obtained by fusion of two GLP-1 analogues with DPP-4 inhibition and human immunoglobulin heavy chain IgG4-Fc fragments. In clinical manifestations, its activity is similar to endogenous GLP-1, with a half-life of 5 days, and can effectively delay renal clearance. The FDA approved the marketing of Dulaglutide subcutaneous injection in September 2014. The European Commission approved the marketing of Dulaglutide subcutaneous injection in Europe in December 2014.
Purity (HPLC) ≥95.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | HGEGTFTSDVSSYLEEQAAKEFIAWLVKGGG |
Sequence(3-letter code) | H-His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Glu-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Gly-Gly-OH |
Peptide Structure | 
|
Molecular Formula | C149H221N37O49 |
Molecular Weight | 3314.62 |
訂購(gòu)聯(lián)系方式：
南京肽研生物生物科技有限公司
手機(jī)號(hào)：19961912513(微信同號(hào))
QQ: 2178255659
郵箱：sales@typeptide.com
聯(lián)系人：顧經(jīng)理
申明：本產(chǎn)品僅供科研使用。
關(guān)鍵字： 923950-08-7;Dulaglutide;杜拉魯肽;多肽;多肽工廠;
肽研生物坐落于國(guó)家級(jí)新區(qū)南京江北新區(qū)新材料產(chǎn)業(yè)園，是一家專業(yè)從事多肽產(chǎn) 品的研發(fā)、生產(chǎn)和銷售以及多肽技術(shù)轉(zhuǎn)讓的高新技術(shù)企業(yè)。公司秉持“誠(chéng)信、嚴(yán) 謹(jǐn)、務(wù)實(shí)”的匠人精神，持續(xù)投入研發(fā)，不斷創(chuàng)新，致力于為科研工作者提供豐 富全面的多肽修飾類型和優(yōu)質(zhì)的產(chǎn)品。