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CST6抗體,Rabbit Polyclonal CST6 Antibody
  • CST6抗體,Rabbit Polyclonal CST6 Antibody
  • CST6抗體,Rabbit Polyclonal CST6 Antibody
  • CST6抗體,Rabbit Polyclonal CST6 Antibody

CST6抗體

價(jià)格 詢價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 湖北
更新日期 2025-05-14
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:CST6抗體英文名稱:Rabbit Polyclonal CST6 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 4000 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 無(wú)靶點(diǎn): CST6
2025-05-14 CST6抗體 Rabbit Polyclonal CST6 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 4000 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/100-1/300 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/2000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human CST6
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human brain tissue using P08208(CST6 Antibody) at dilution 1/70. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P08208(CST6 Antibody) at dilution 1/70. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于CST6抗體的示例參考文獻(xiàn)(內(nèi)容為模擬概括,建議通過(guò)學(xué)術(shù)數(shù)據(jù)庫(kù)核實(shí)最新研究):

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1. **文獻(xiàn)名稱**:*Cystatin 6 (CST6) as a biomarker in serous ovarian carcinoma: Immunohistochemical analysis*

**作者**:Zhang Y, et al. (2017)

**摘要**:研究通過(guò)CST6抗體進(jìn)行免疫組化分析,發(fā)現(xiàn)CST6在卵巢癌組織中高表達(dá),且與患者預(yù)后不良相關(guān),提示其可能作為潛在治療靶點(diǎn)。

2. **文獻(xiàn)名稱**:*Development of a monoclonal antibody against CST6 and its application in breast cancer progression*

**作者**:Wang L, et al. (2015)

**摘要**:開發(fā)了針對(duì)CST6的單克隆抗體,實(shí)驗(yàn)表明抑制CST6可減少乳腺癌細(xì)胞侵襲,抗體為研究CST6在腫瘤轉(zhuǎn)移中的作用提供了工具。

3. **文獻(xiàn)名稱**:*Epigenetic silencing of CST6 in oral squamous cell carcinoma: Validation by antibody-based assays*

**作者**:Chen H, et al. (2020)

**摘要**:利用CST6抗體驗(yàn)證口腔鱗癌中CST6的表觀遺傳沉默,發(fā)現(xiàn)其啟動(dòng)子甲基化導(dǎo)致表達(dá)下調(diào),與腫瘤分化程度相關(guān)。

4. **文獻(xiàn)名稱**:*CST6 as a prognostic marker in head and neck cancer: Correlation studies using antibody-mediated detection*

**作者**:Liu X, et al. (2018)

**摘要**:通過(guò)抗體檢測(cè)頭頸癌患者組織中CST6水平,發(fā)現(xiàn)低表達(dá)與淋巴結(jié)轉(zhuǎn)移和生存率下降顯著相關(guān),支持其作為預(yù)后標(biāo)志物。

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**備注**:以上內(nèi)容為示例,實(shí)際文獻(xiàn)需通過(guò)PubMed、Google Scholar或Web of Science等平臺(tái)檢索關(guān)鍵詞(如“CST6 antibody”“Cystatin 6 cancer”)獲取最新研究。

       

背景信息

The cystatin superfamily comprises cysteine protease inhibitors involved in regulating proteolytic activity. Cystatin 6 (CST6), a member of the type 1 cystatin family, is encoded by the *CST6* gene and functions as an extracellular inhibitor of cathepsins, enzymes linked to tissue remodeling, inflammation, and cancer progression. Unlike other cystatins, CST6 contains a unique signal peptide for secretion and a conserved cystatin domain, enabling extracellular protease regulation.

Research highlights CST6's dual role in cancer biology. It exhibits tumor-suppressive properties in some contexts by inhibiting cathepsin-mediated invasion and metastasis, notably in breast and ovarian cancers. However, its overexpression in other malignancies, such as oral squamous cell carcinoma, correlates with poor prognosis, suggesting context-dependent functions. CST6 is also implicated in skin barrier formation and immunological processes.

CST6 antibodies are critical tools for detecting CST6 expression in tissues or biofluids via immunohistochemistry, Western blotting, or ELISA. These antibodies aid in studying CST6's role in disease mechanisms, validating its potential as a diagnostic or prognostic biomarker, and exploring therapeutic strategies targeting protease pathways. Commercial CST6 antibodies are typically validated for specificity against recombinant or endogenous proteins, though variability in experimental conditions requires careful optimization. Ongoing research seeks to clarify CST6's regulatory networks and clinical relevance across pathologies.

       
關(guān)鍵字: CST6抗體;CST6;CST6 Antibody;

公司簡(jiǎn)介

湖北瑞和寧生物科技有限公司研究創(chuàng)新能力, 擁有完整、科學(xué)、質(zhì)量管理體系。并不斷致力于技術(shù)創(chuàng)新,產(chǎn)品創(chuàng)新和管理創(chuàng)新,贏得了國(guó)內(nèi)外廣大用戶的信任。
成立日期 2024-06-24 (2年) 注冊(cè)資本 50萬(wàn)(元)
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬(wàn)以內(nèi)
主營(yíng)行業(yè) 中間體,化學(xué)試劑 經(jīng)營(yíng)模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 湖北瑞和寧生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊(cè)資本:50萬(wàn)(元)
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營(yíng)產(chǎn)品:中間體。試劑
  • 公司地址:江漢區(qū)
詢盤

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CST6抗體相關(guān)廠家報(bào)價(jià)

產(chǎn)品名稱 價(jià)格   公司名稱 報(bào)價(jià)日期
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費(fèi)雪(杭州)醫(yī)學(xué)研究有限公司
2025-07-28
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湖北艾普蒂生物工程有限公司
2025-06-04
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