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CAPG抗體,Rabbit Polyclonal CAPG Antibody
  • CAPG抗體,Rabbit Polyclonal CAPG Antibody
  • CAPG抗體,Rabbit Polyclonal CAPG Antibody
  • CAPG抗體,Rabbit Polyclonal CAPG Antibody

CAPG抗體

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 湖北
更新日期 2025-05-13
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:CAPG抗體英文名稱:Rabbit Polyclonal CAPG Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 3729 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: CAPG
2025-05-13 CAPG抗體 Rabbit Polyclonal CAPG Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 3729 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesMCP; AFCP
WB Predicted band size38 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human CAPG
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Mouse lung tissue, human fetal lung tissue, hela cells, Primary antibody: P07757(CAPG Antibody) at dilution 1/700, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P07757(CAPG Antibody) at dilution 1/35. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P07757(CAPG Antibody) at dilution 1/35. (Original magnification: ×200)    


           

參考文獻

以下是關(guān)于CAPG抗體的3篇參考文獻示例(注:以下內(nèi)容為模擬生成,僅供參考):

1. **文獻名稱**: "CAPG as a Biomarker in Triple-Negative Breast Cancer: Immunohistochemical Analysis Using a Novel Monoclonal Antibody"

**作者**: Smith, J.R., et al.

**摘要**: 該研究開發(fā)了一種新型抗CAPG單克隆抗體,并通過免疫組化分析發(fā)現(xiàn)CAPG在三陰性乳腺癌組織中高表達,與腫瘤轉(zhuǎn)移和不良預(yù)后顯著相關(guān)。結(jié)果表明CAPG可能作為潛在的治療靶點或診斷標志物。

2. **文獻名稱**: "Autoantibodies to Cytoskeletal Protein CAPG in Rheumatoid Arthritis: Clinical Associations and Pathogenic Role"

**作者**: Tanaka, M., et al.

**摘要**: 研究檢測了類風濕性關(guān)節(jié)炎(RA)患者血清中的CAPG自身抗體水平,發(fā)現(xiàn)其與疾病活動度和關(guān)節(jié)破壞程度呈正相關(guān)。實驗表明CAPG抗體可能通過激活NF-κB通路加劇炎癥反應(yīng),提示其在RA發(fā)病機制中的作用。

3. **文獻名稱**: "Development of a High-Sensitivity ELISA for CAPG Detection in Pancreatic Cancer Serum Samples"

**作者**: Wang, L., et al.

**摘要**: 該團隊利用CAPG多克隆抗體建立了一種高靈敏度ELISA檢測方法,證實胰腺癌患者血清CAPG水平顯著高于健康對照組,且與腫瘤分期相關(guān)。該方法為無創(chuàng)診斷胰腺癌提供了新策略。

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*注:以上文獻信息為示例性模擬,實際研究中請通過學(xué)術(shù)數(shù)據(jù)庫(如PubMed、Web of Science)以關(guān)鍵詞“CAPG antibody”“CAPG biomarker”等檢索最新文獻。*

       

背景信息

CAPG (macrophage-capping protein) is an actin-binding protein belonging to the gelsolin superfamily, primarily involved in regulating actin filament dynamics. It modulates cell membrane architecture, motility, and intracellular trafficking by capping the barbed ends of actin filaments, thereby stabilizing cytoskeletal structures. CAPG is expressed in various tissues, with notable roles in immune cells (e.g., macrophages, neutrophils) and cancer cells. Its dual localization in the cytoplasm and nucleus suggests additional functions in transcriptional regulation and chromatin remodeling.

CAPG antibodies are widely used in research to investigate its expression patterns and mechanistic roles. Overexpression of CAPG has been linked to tumor progression, metastasis, and poor prognosis in cancers such as breast, prostate, and colorectal cancer, making it a potential biomarker or therapeutic target. In immunology, CAPG antibodies help study its involvement in inflammatory responses and phagocytosis.

Commercially available CAPG antibodies are developed for techniques like Western blotting, immunohistochemistry, and immunofluorescence. However, specificity validation remains crucial due to structural similarities within the gelsolin family. Recent studies also explore CAPG's interaction with viral pathogens and its role in neurodegenerative diseases, expanding its relevance in biomedical research.

       
關(guān)鍵字: CAPG抗體;CAPG;CAPG Antibody;

公司簡介

湖北瑞和寧生物科技有限公司研究創(chuàng)新能力, 擁有完整、科學(xué)、質(zhì)量管理體系。并不斷致力于技術(shù)創(chuàng)新,產(chǎn)品創(chuàng)新和管理創(chuàng)新,贏得了國內(nèi)外廣大用戶的信任。
成立日期 2024-06-24 (1年) 注冊資本 50萬(元)
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 中間體,化學(xué)試劑 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 湖北瑞和寧生物科技有限公司
VIP 1年
  • 公司成立:1年
  • 注冊資本:50萬(元)
  • 企業(yè)類型:有限責任公司(自然人投資或控股)
  • 主營產(chǎn)品:中間體。試劑
  • 公司地址:江漢區(qū)
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