
TSLP分子信息
英文名稱(chēng):Thymic stromal lymphopoietin
中文名稱(chēng):胸腺基質(zhì)淋巴細(xì)胞生成素
靶點(diǎn)別稱(chēng):TSLP
物種:Human / Mouse / Cynomolgus / Rat
屬性:Protein
標(biāo)記:Biotin-labeled / Unconjugated
內(nèi)毒素(Endotoxin)
Less than 0.1 EU per μg by the LAL method.
無(wú)菌(Sterility)
The sterility testing was performed by membrane filtration method.
支原體(Mycoplasma)
Negative.
純度(Purity)
>90% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(chǔ)(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
1. -20°C to -70°C for 24 months in lyophilized state;
2. -70°C for 24 months under sterile conditions after reconstitution.


TSLP分子背景
胸腺基質(zhì)淋巴生成素(TSLP)是一種上皮細(xì)胞衍生的細(xì)胞因子,參與炎癥性皮膚病的病理過(guò)程,并在上皮細(xì)胞中廣泛表達(dá)。人TSLP cDNA編碼一個(gè)159個(gè)氨基酸(aa)殘基的前體蛋白,其信號(hào)序列為28aa(4,5)。人類(lèi)TSLP已被證明可以發(fā)展非破壞性中樞耐受,放大上皮誘導(dǎo)的類(lèi)別轉(zhuǎn)換,誘導(dǎo)特應(yīng)性疾病,并維持腸道非炎癥環(huán)境。在對(duì)人TSLP有反應(yīng)的多種細(xì)胞中,CD11c+樹(shù)突狀細(xì)胞是特征最明顯的靶細(xì)胞。
TSLP產(chǎn)品用戶(hù)評(píng)價(jià)

關(guān)鍵字: TSLP;TSLP蛋白;TSLP重組蛋白;TSLP抗原;小鼠TSLP;
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