中文名：N-羥基琥珀酰亞胺

英文名：N-Hydroxysuccinimide

中文別名：N-羥基丁二酰亞胺 | 1-羥基-2,5-吡咯烷二酮

英文別名：1-hydroxypyrrolidine-2,5-dione | 1-Hydroxy-2,5-pyrrolidinedione | 1-Hydroxysuccinimide | HOSu | Hydroxysuccinimide

純度：98%

貨號：H109330

包裝：100g、25g、500g

Cas號：6066-82-6

存儲溫度：2-8°C儲存,充氬

產(chǎn)品介紹：

N-Hydroxysuccinimide, commonly known as NHS, is a hydroxylated succinimide that is widely used in the activation of carboxylic acids to NHS-esters to promote coupling with nucleophiles. This approach is most commonly employed in activating the free acid forms of fluorophores for promoting conjμgation of these fluorophores to amine residues of proteins. Use of NHS ester activation has also been described in the synthesis of N-acyl amino acids.Useful in the carbodiimide method for improved amidations and peptide couplings. N-羥基琥珀酰亞胺可以在存在二環(huán)己基碳二亞胺的條件下在羧酸中通過脫水反應(yīng)合成N-羥基琥珀酰亞胺酯。 N-羥基琥珀酰亞胺已用于中間介質(zhì)的合成如： · N-丁二酰亞胺3-(二-三-丁基氟硅烷）苯甲酸 · 4-[2,2-雙[(對-甲苯磺酰)-甲基]乙酰]苯甲酸-NHS酯 · N-丁二酰亞胺3-碘苯甲酸 它還用于微流體整合的表面等離子體共振（SPR）平臺的微通道的表面修飾的實驗方法中，用于對細菌病原體進行檢測和定量。 碳二亞胺方法中使用的添加劑用于改良的酰胺化[1]及肽偶聯(lián)。

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