Product Name：Bivalirudin
CAS No.：128270-60-0
Synonyms：BG 8967；Hirulog；Hirulog I；比伐蘆定
Catalog No.：160P10
Brand：HongTide（上海鴻肽）
Description：比伐蘆定是一種人工合成的抗凝血藥物，是水蛭素的20肽類(lèi)似物，肽鏈中含有較多的羧基，是一條酸性多肽，于2000年獲準(zhǔn)在美國(guó)上市。比伐蘆定能與凝血酶催化位點(diǎn)和陰離子外結(jié)合位點(diǎn)發(fā)生特異性結(jié)合，直接抑制凝血酶的活性，從而抑制凝血酶所催化和誘導(dǎo)的反應(yīng)，其作用是可逆的。比伐蘆定主要作為抗凝劑用于成人擇期經(jīng)皮冠狀動(dòng)脈介入治療(PCI)。
Bivalirudin is a synthetic anticoagulant drug, which is a 20-peptide analogue of hirudin. The peptide chain contains more carboxyl groups, and is an acidic peptide. It was approved to be listed in the United States in 2000. Bivalirudin can bind specifically with the thrombin catalytic site and the anion external binding site, directly inhibit the activity of thrombin, and thus inhibit the reaction catalyzed and induced by thrombin, and its effect is reversible. Bivalirudin is mainly used as an anticoagulant in adult selective percutaneous coronary intervention (PCI).
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | d-FPRPGGGGNGDFEEIPEEYL |
Sequence(3-letter code) | D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH |
Peptide Structure | 
|
Molecular Formula | C98H138N24O33 |
Molecular Weight | 2180.32 |
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關(guān)鍵字： 128270-60-0;比伐蘆定;Bivalirudin;多肽;藥物多肽;
上海鴻肽生物科技有限公司（簡(jiǎn)稱：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷(xiāo)售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來(lái)，秉持“用質(zhì)量作船， 以服務(wù)為帆，為科研服務(wù)”的企業(yè)理念，為國(guó)內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。