硫酸長(zhǎng)春堿
產(chǎn)品名稱：硫酸長(zhǎng)春堿,長(zhǎng)春堿
標(biāo)準(zhǔn)：USP31/EP6.0
CAS號(hào)：143-67-9
EC 號(hào)：205-6-6-0
分子式：C46H58N4O9•H2SO4
分子量：909.06
酸度或堿度：PH3.5 - 5.0
含量：95.0％
熔點(diǎn)：267℃
相關(guān)物質(zhì)：不超過(guò)1.0％
總雜質(zhì)：不超過(guò)3.0％
灼燒殘?jiān)翰怀^(guò)0.1％
外觀：本品為白色或類白色的疏松狀或無(wú)定形固體，有引濕性，遇光或熱易變黃。
水溶性：≥1 g/100在24.5℃毫升
功能與用途：主要用于實(shí)體瘤的治療。對(duì)惡性淋巴瘤、睪丸腫瘤、絨毛膜癌療效較好，對(duì)肺癌、乳腺癌、卵巢癌、皮膚癌、腎母細(xì)胞瘤及單核細(xì)胞白血病也有一定療效。
霍其金病及惡性淋巴瘤，亦可用于治療絨毛膜上皮癌與乳腺癌
分子結(jié)構(gòu)式：
硫酸長(zhǎng)春堿
Vinblastina solfato，Sulfato de vinblastina，Vincaleukoblastine sulfate，vincaleukoblastine，Sulfate de vinblastine
Product Name: Vinblastine Sulfate
Standard: USP31/EP6.0
CAS No: 143-67-9
EC No: 205-6-6-0
Molecular Formula: C46H58N4O9·H2SO4
Molecular Weight: 909.06
Acidity or Alkalinity: PH3.5-5.0
Assay: 95.0%
Specific Rotation: -21.7°(c=2, CH3OH 21℃)
Melting Point: 267℃
Maximum Related substances：not more than 1.0%
Total impurities: not more than 3.0%
Residue on ignition: not more than 0.1%
Appearance: White crystalline powder, odourlessness, turns yellow when meeting light or heat.
Water Solubility: ≥1 g/100 ml at 24.5℃
Function and Use: It is alkaloid which has inhibitory to the tumor for cycling medicine. It suppresses spindle formation of multiplication cell as raw material for malignant lymphoma, specially for cell sarcoma of lymph reticular, Hodgkin’s disease, chorioepithelioma, breast cancer, pate cancer, oropharynx cancer, nerve metrocyte cancer, uninuclear cell leukemia, lung cancer, carcinoma of cervix and the digestive tract tumor curative.
Molecular Structural Formula: