一、中文名稱(chēng)：
Recombinant HPV18 L1Major capsid protein L1 Protein, C-His，重組HPV18 L1/主要衣殼蛋白L1蛋白，C-His，精品重組蛋白
二、產(chǎn)品描述
作為HPV18型衣殼的核心結(jié)構(gòu)蛋白，L1能夠自組裝形成病毒樣顆粒（VLPs），其表面展示的構(gòu)象依賴(lài)性抗原表位可被宿主免疫系統(tǒng)（如B細(xì)胞受體和模式識(shí)別受體）特異性識(shí)別，模擬天然病毒顆粒的免疫原性，從而激活適應(yīng)性免疫應(yīng)答，誘導(dǎo)高滴度的型別特異性中和抗體，為HPV預(yù)防性疫苗（如多價(jià)疫苗）的研發(fā)提供關(guān)鍵抗原基礎(chǔ)。
三、產(chǎn)品詳情
名稱(chēng)：Recombinant HPV18 L1Major capsid protein L1 Protein, C-His，重組HPV18 L1/主要衣殼蛋白L1蛋白，C-His，精品重組蛋白，活性蛋白，重組蛋白
貨號(hào): YVV11803
表達(dá)系統(tǒng): E. coli
種屬: Human papillomavirus type 18 (HPV18)
蛋白長(zhǎng)度: Thr71-Lys568
預(yù)測(cè)分子量: 56.45 kDa
性質(zhì): Recombinant
內(nèi)毒素水平: Please contact with the lab for this information.
純度: >90% as determined by SDS-PAGE.
Accession號(hào): NP_040317.1
應(yīng)用: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
狀態(tài): Lyophilized
保存溶液: Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
重懸: Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
運(yùn)輸: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
穩(wěn)定性和存儲(chǔ): Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名: L1 protein, L1
Prospects for cervical cancer prevention by human papillomavirus vaccination. PMID: 17079437
Reducing the economic burden of HPV-related diseases. PMID: 18463361
Methylation of human papillomavirus 16, 18, 31, and 45 L2 and L1 genes and the cellular DAPK gene: Considerations for use as biomarkers of the progression of cervical neoplasia. PMID: 24314662
Methylation of the human papillomavirus-18 L1 gene: a biomarker of neoplastic progression? PMID: 16472835
Comparative Evaluation of Human Papillomavirus Type 16 L1 Protein Expressed in Plasmid- and Baculovirus-Based Systems in Insect Cells. PMID: 32621447
Multivalent human papillomavirus l1 DNA vaccination utilizing electroporation. PMID: 23536912
A method for removing contaminating protein during purification of human papillomavirus type 18 L1 protein from Saccharomyces cerevisiae. PMID: 20162405
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