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  2. 多肽產(chǎn)品
  3. 多肽及其衍生物
  4. 其他
  5. LEP(116-130)(mouse)

LEP(116-130)(mouse) 是一種合成的瘦素肽片段。

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Custom Peptide Synthesis

LEP(116-130)(mouse) Chemical Structure

LEP(116-130)(mouse) Chemical Structure

CAS No. : 258276-95-8

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規(guī)格 價格 是否有貨 數(shù)量
1 mg ￥800
In-stock
5 mg ￥2400
In-stock
10 mg ￥3900
In-stock
50 mg   詢價  
100 mg   詢價  

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MCE 顧客使用本產(chǎn)品發(fā)表的 1 篇科研文獻

  • 生物活性

  • 實驗參考方法

  • 純度 & 產(chǎn)品資料

  • 參考文獻

生物活性

LEP(116-130)(mouse) is a synthetic leptin peptide fragment.

體外研究
(In Vitro)

LEP-(116-130) (300 μM) is unable to inhibit AP-OB binding[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
體內(nèi)研究
(In Vivo)

LEP-(116-130) (1 mg, i.p.) results in a reduced rate of body weight gain in the presence of increased food intake compared with vehicle-injcted control mice. LEP-(116-130) significantly reduces blood glucose levels by appr 100 mg/dL. Administration of LEP-(116-130) to wild-type (+/+) C57BLKS/J-m mice for 4 or 7 days has no effect on their ability to thermoregulate[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

1560.73

Formula

C64H109N19O24S
CAS 號
性狀

固體

顏色

White to off-white

Sequence

Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-NH2
Sequence Shortening

SCSLPQTSGLQKPES-NH2
運輸條件

Room temperature in continental US; may vary elsewhere.
儲存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

純度 & 產(chǎn)品資料
參考文獻
Animal Administration
[1]

Blood is drawn from the tail vein of each mouse 2 h before the onset of the dark period at the beginning of the study (day 0) and after 2, 4, and 6 days of treatment with 1 mg/day i.p. LEP-(116-130). Blood glucose levels are determined with a Glucometer Elite blood glucose monitor. After 4 and 7 days of treatment with 1 mg/day i.p. LEP-(116-130), sensitivity to cold is examined by placing the mice without food or water in a cold room with an ambient temperature of 4°C. Body temperature is measured with a rectal probe every hour for 4 h.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
參考文獻

LEP(116-130)(mouse) 相關(guān)分類

  • 摩爾計算器

  • 稀釋計算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

質(zhì)量   濃度   體積   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

濃度 (start) × 體積 (start) = 濃度 (final) × 體積 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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產(chǎn)品名稱：
LEP(116-130)(mouse)
目錄號：
HY-P1027
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